Evans Matthew D, Baumgartner J Craig, Khemaleelakul Saeng-usa, Xia Tian
Oregon Health & Science University, Portland 97201, USA.
J Endod. 2003 May;29(5):338-9. doi: 10.1097/00004770-200305000-00005.
The purpose of this study was to evaluate the antibacterial efficacy of an intracanal medication composed of calcium hydroxide with 2% chlorhexidine. Dentin from 24 bovine incisors was used. The incisors were made into standardized cylindrical segments of dentin and infected with Enterococcus faecalis. They were then treated with an intracanal paste composed of calcium hydroxide and sterile water or an intracanal paste composed of calcium hydroxide and 2% chlorhexidine for 1 week. Dentin shavings were collected, suspended in solution, and spread on brain-heart infusion agar. After incubation, colony-forming units were enumerated. The amount of bacteria per mg of dentin was determined. The calcium hydroxide paste with 2% chlorhexidine was significantly more effective at killing E. faecalis in the dentinal tubules than calcium hydroxide with water.
本研究的目的是评估由氢氧化钙与2%洗必泰组成的根管内用药的抗菌效果。使用了来自24颗牛切牙的牙本质。将切牙制成标准化的圆柱形牙本质段，并感染粪肠球菌。然后用由氢氧化钙和无菌水组成的根管糊剂或由氢氧化钙和2%洗必泰组成的根管糊剂处理1周。收集牙本质碎屑，悬浮于溶液中，并涂布于脑心浸液琼脂上。孵育后，计数菌落形成单位。测定每毫克牙本质中的细菌数量。含2%洗必泰的氢氧化钙糊剂在杀死牙本质小管中的粪肠球菌方面比含水的氢氧化钙显著更有效。
