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乙醇栓塞治疗耳廓动静脉畸形:17 例初步结果。

Ethanol embolization of auricular arteriovenous malformations: preliminary results of 17 cases.

机构信息

Department of Radiology, Ninth People's Hospital, Shanghai Jiao Tong University, Shanghai, P.R. China.

出版信息

AJNR Am J Neuroradiol. 2009 Oct;30(9):1679-84. doi: 10.3174/ajnr.A1687. Epub 2009 Jul 17.

Abstract

BACKGROUND AND PURPOSE

Because of the relatively rare and extremely varied clinical presentations, arteriovenous malformations (AVMs) involving the auriculae are technically challenging clinical entities to diagnose and, ultimately, manage. The purpose of our study was to present our initial experience of ethanol embolization in a series of 17 patients with auricular AVMs and assess the interim therapeutic outcomes of this method.

MATERIALS AND METHODS

Our study group consisted of 17 patients. Transcatheter arterial embolization and/or direct percutaneous puncture embolization were performed. Pure or diluted ethanol was manually injected. Follow-up evaluation was obtained on the basis of physical examination and angiography at 3- to 4-month intervals and telephone questionnaire at 1-month intervals in all patients.

RESULTS

During the 29 ethanol embolization procedures, the amount of ethanol used ranged from 4 to 65 mL. The obliteration of ulceration, hemorrhage, pain, infection, pulsation, and bruit in most of the patients was obtained. The reduction of redness, swelling, and warmth was achieved in all of the patients, and 15 of the patients achieved downstaging of the Schobinger status. According to the angiographic findings, AVMs were devascularized 100% in 3 patients, 76% to 99% in 5 patients, 50% to 75% in 6 patients, and less than 50% in 3 patients. The most common complications were reversible necrosis and blister.

CONCLUSIONS

Ethanol embolization has proved efficacious and safe in the treatment of auricular AVMs and has the potential to be accepted as the primary mode of therapy in the management of these lesions.

摘要

背景与目的

由于涉及耳的动静脉畸形(AVM)的临床表现相对罕见且极其多样,因此在诊断和最终管理方面具有技术挑战性。我们研究的目的是介绍我们在 17 例耳 AVM 患者中进行乙醇栓塞的初步经验,并评估该方法的中期治疗效果。

材料与方法

我们的研究组包括 17 例患者。经导管动脉栓塞和/或直接经皮穿刺栓塞。手动注射纯乙醇或稀释乙醇。所有患者均在 3-4 个月的间隔期进行体格检查和血管造影随访,并在 1 个月的间隔期进行电话问卷调查。

结果

在 29 次乙醇栓塞过程中,使用的乙醇量从 4 到 65 毫升不等。大多数患者的溃疡、出血、疼痛、感染、搏动和杂音得到了缓解。所有患者的红肿、肿胀和发热均减轻,Schobinger 分期中有 15 例患者降期。根据血管造影结果,3 例患者 AVM 完全去血管化(100%),5 例患者为 76%至 99%,6 例患者为 50%至 75%,3 例患者<50%。最常见的并发症是可逆性坏死和水疱。

结论

乙醇栓塞已被证明在治疗耳 AVM 方面是有效且安全的,并且有可能被接受为治疗这些病变的主要治疗方式。

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