Willems Daniëlle C M, Joore Manuela A, Nieman Fred H M, Severens Johan L, Wouters Emiel F M, Hendriks Johannes J E
Department of Clinical Epidemiology and Medical Technology Assessment, Maastricht University Medical Centre, Maastricht, The Netherlands.
Int J Technol Assess Health Care. 2009 Jul;25(3):391-9. doi: 10.1017/S0266462309990171.
This study explores several variables of the EQ-5D child version, a multi-attribute utility instrument, in children with chronic conditions.
A convenience sample was selected from hospital outpatient records and school records. The sample included children aged 7-18 years with the following chronic conditions: asthma, rheumatic disorders, diabetes, and speech/language and/or hearing disorders. The practicality, convergent validity, and discriminant power were compared with a generic quality of life questionnaire for children (TACQOL) and the 2-week test-retest reliability was assessed.
A total of 182 children or their parents completed the first questionnaire and 161 children/parents completed both questionnaires. The practicality of the EQ-5D was good. Low to moderate correlations were found between the utilities and VAS scores and the TACQOL scales. The discriminant power of the EQ-5D items was low overall and was greater for children with a rheumatic disorder than for children with the other conditions. In the subset of children who experienced no health change between the test and the retest, the reliability of the EQ-5D was moderate to high.
The EQ-5D seems suitable for children, although the use of an additional disease-specific questionnaire is still recommended. The EQ-5D seems the most suitable for children with a chronic physical condition and appears to be reliable for children with a stable health status.
本研究探讨了多属性效用工具EQ-5D儿童版在慢性病患儿中的几个变量。
从医院门诊记录和学校记录中选取便利样本。样本包括7至18岁患有以下慢性病的儿童：哮喘、风湿性疾病、糖尿病以及言语/语言和/或听力障碍。将其实用性、收敛效度和区分能力与儿童通用生活质量问卷（TACQOL）进行比较，并评估其两周重测信度。
共有182名儿童或其父母完成了第一份问卷，161名儿童/父母完成了两份问卷。EQ-5D的实用性良好。效用值与视觉模拟量表（VAS）得分以及TACQOL量表之间存在低至中度的相关性。EQ-5D项目的区分能力总体较低，风湿性疾病患儿的区分能力高于其他疾病患儿。在测试和重测期间健康状况无变化的儿童子集中，EQ-5D的信度为中度至高度。
EQ-5D似乎适用于儿童，不过仍建议使用额外的疾病特异性问卷。EQ-5D似乎最适用于患有慢性身体疾病的儿童，且对健康状况稳定的儿童似乎具有可靠性。
