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A synthetic enkephalin analogue with prolonged parenteral and oral analgesic activity.

作者信息

Roemer D, Buescher H H, Hill R C, Pless J, Bauer W, Cardinaux F, Closse A, Hauser D, Huguenin R

出版信息

Nature. 1977 Aug 11;268(5620):547-9. doi: 10.1038/268547a0.

DOI:10.1038/268547a0

PMID:196219

Abstract

摘要

相似文献

A synthetic enkephalin analogue with prolonged parenteral and oral analgesic activity.

Nature. 1977 Aug 11;268(5620):547-9. doi: 10.1038/268547a0.

Interactions of leucine enkephalin and narcotics with opioid receptors.

Mol Pharmacol. 1981 Mar;19(2):236-41.

Morphine and enkephalin: analgesic and epileptic properties.

Science. 1977 Jul 1;197(4298):83-6. doi: 10.1126/science.867056.

Opioid receptors inhibit the adenylate cyclase in guinea pig cochleas.

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Opiates and enkephalins: a common binding site mediates their analgesic actions in rats.

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Neuroanatomical focus for morphine and enkephalin-induced hypermotility.

Nature. 1977 Feb 17;265(5595):645-7. doi: 10.1038/265645a0.

Action of enkephalin analogues and morphine on brain acetylcholine release: differential reversal by naloxone and an opiate pentapeptide.

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Leu-enkephalin-stimulated growth hormone and prolactin release in the rat: comparison with the effect of morphine.

Life Sci. 1977 Jun 15;20(12):2041-5. doi: 10.1016/0024-3205(77)90184-9.

Naloxone-induced withdrawal syndrome after administration of selective opioid agonists or after activation of the endogenous enkephalinergic system.

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Investigation of action of enkephalin on the spontaneous and evoked release of acetylcholine from rat cortical and striatal slices.

Br J Pharmacol. 1980;71(1):211-7. doi: 10.1111/j.1476-5381.1980.tb10928.x.

Action of enkephalin analogues and morphine on brain acetylcholine release: differential reversal by naloxone and an opiate pentapeptide.

Br J Pharmacol. 1980;71(1):201-10. doi: 10.1111/j.1476-5381.1980.tb10927.x.

Leucine-enkephalin and methionine-enkephalin produce opposing effects on plasma corticosterone levels in ether-stressed mice.

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A synthetic enkephalin analogue with prolonged parenteral and oral analgesic activity.

作者信息

Roemer D, Buescher H H, Hill R C, Pless J, Bauer W, Cardinaux F, Closse A, Hauser D, Huguenin R

出版信息

Nature. 1977 Aug 11;268(5620):547-9. doi: 10.1038/268547a0.

DOI:10.1038/268547a0

PMID:196219

Abstract

摘要

相似文献

A synthetic enkephalin analogue with prolonged parenteral and oral analgesic activity.

Nature. 1977 Aug 11;268(5620):547-9. doi: 10.1038/268547a0.

Interactions of leucine enkephalin and narcotics with opioid receptors.

Mol Pharmacol. 1981 Mar;19(2):236-41.

Morphine and enkephalin: analgesic and epileptic properties.

Science. 1977 Jul 1;197(4298):83-6. doi: 10.1126/science.867056.

Opioid receptors inhibit the adenylate cyclase in guinea pig cochleas.

Brain Res. 1987 Sep 22;421(1-2):336-42. doi: 10.1016/0006-8993(87)91303-5.

Opiates and enkephalins: a common binding site mediates their analgesic actions in rats.

Life Sci. 1981 Aug 24;29(8):843-51. doi: 10.1016/0024-3205(81)90041-2.

Role of mu and delta receptors in the supraspinal and spinal analgesic effects of [D-Pen2, D-Pen5]enkephalin in the mouse.

J Pharmacol Exp Ther. 1987 May;241(2):393-400.

Neuroanatomical focus for morphine and enkephalin-induced hypermotility.

Nature. 1977 Feb 17;265(5595):645-7. doi: 10.1038/265645a0.

Action of enkephalin analogues and morphine on brain acetylcholine release: differential reversal by naloxone and an opiate pentapeptide.

Br J Pharmacol. 1980;71(1):201-10. doi: 10.1111/j.1476-5381.1980.tb10927.x.

Leu-enkephalin-stimulated growth hormone and prolactin release in the rat: comparison with the effect of morphine.

Life Sci. 1977 Jun 15;20(12):2041-5. doi: 10.1016/0024-3205(77)90184-9.

Naloxone-induced withdrawal syndrome after administration of selective opioid agonists or after activation of the endogenous enkephalinergic system.

Prog Clin Biol Res. 1990;328:531-4.

引用本文的文献

A tetrapeptide class of biased analgesics from an Australian fungus targets the µ-opioid receptor.

Proc Natl Acad Sci U S A. 2019 Oct 29;116(44):22353-22358. doi: 10.1073/pnas.1908662116. Epub 2019 Oct 14.

Peptides and proteins as drugs.

Pharm Res. 1985 Jul;2(4):151-6. doi: 10.1023/A:1016327803573.

Opioid glycopeptide analgesics derived from endogenous enkephalins and endorphins.

Future Med Chem. 2012 Feb;4(2):205-26. doi: 10.4155/fmc.11.195.

Biomimetic materials for tissue engineering.

Adv Drug Deliv Rev. 2008 Jan 14;60(2):184-98. doi: 10.1016/j.addr.2007.08.041. Epub 2007 Nov 28.

Pituitary. 2000 May;2(4):253-60. doi: 10.1023/a:1009957015563.

Mechanism of mu-opioid receptor-mediated presynaptic inhibition in the rat hippocampus in vitro.

J Physiol. 1993 Oct;470:539-58. doi: 10.1113/jphysiol.1993.sp019874.

The distribution of adrenoceptors and other drug receptors between the two ends of the rat vas deferens as revealed by selective agonists and antagonists.

Br J Pharmacol. 1980;71(2):445-58. doi: 10.1111/j.1476-5381.1980.tb10957.x.

Investigation of action of enkephalin on the spontaneous and evoked release of acetylcholine from rat cortical and striatal slices.

Br J Pharmacol. 1980;71(1):211-7. doi: 10.1111/j.1476-5381.1980.tb10928.x.

Action of enkephalin analogues and morphine on brain acetylcholine release: differential reversal by naloxone and an opiate pentapeptide.

Br J Pharmacol. 1980;71(1):201-10. doi: 10.1111/j.1476-5381.1980.tb10927.x.

Leucine-enkephalin and methionine-enkephalin produce opposing effects on plasma corticosterone levels in ether-stressed mice.

Br J Pharmacol. 1980 Dec;70(4):509-11. doi: 10.1111/j.1476-5381.1980.tb09767.x.