Minetto Marco Alessandro, Botter Alberto
Division of Endocrinology and Metabolism, Department of Internal Medicine, University of Turin, C.so Dogliotti 14, 10126 Torino, Italy.
Muscle Nerve. 2009 Oct;40(4):535-44. doi: 10.1002/mus.21382.
To explore the efficacy of muscle motor point stimulation in eliciting muscle cramps, 11 subjects underwent eight sessions of electrical stimulation of the following muscles bilaterally: abductor hallucis flexor hallucis brevis, and both heads of the gastrocnemius muscles. Bursts of 150 square wave stimuli (duration: 152 micros; current intensity: 30% supramaximal) were applied. The stimulation frequency was increased from 4 pulses per second (pps) at increments of 2 pps until a cramp was induced. The number of cramps that could be elicited was smaller in flexor hallucis brevis than in abductor hallucis (16 vs. 22 out of 22 trials each; P < 0.05) and in the lateral gastrocnemius than in the medial gastrocnemius (5 vs. 20 out of 22 trials each; P < 0.0001). We show that leg and foot muscles have different cramp susceptibility, and the intermuscle variability in the elicitability profile for electrically induced cramps supports the use of the proposed method for cramp research.
为探究肌肉运动点刺激引发肌肉痉挛的效果，11名受试者双侧接受了以下肌肉的八次电刺激：拇展肌、拇短屈肌以及腓肠肌的两个头。施加150次方波刺激脉冲串（持续时间：152微秒；电流强度：最大刺激强度的30%）。刺激频率从每秒4次脉冲（pps）开始，以每秒2次脉冲的增量增加，直至诱发痉挛。拇短屈肌诱发的痉挛次数比拇展肌少（每次22次试验中分别为16次和22次；P<0.05），外侧腓肠肌诱发的痉挛次数比内侧腓肠肌少（每次22次试验中分别为5次和20次；P<0.0001）。我们表明，腿部和足部肌肉具有不同的痉挛易感性，电诱发痉挛的诱发能力在肌肉间的变异性支持了所提出的痉挛研究方法的应用。
