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阿根廷布宜诺斯艾利斯省东南部的小儿包虫病

Pediatric hydatidosis in the south-east of the Buenos Aires province, Argentina.

作者信息

Dopchiz M C, Elissondo M C, Andresiuk M V, Maiorini E, Gutiérrez A M, Muzulin P M, Rosenzvit M C, Lavallén C M, Denegri G

机构信息

Laboratorio de Zoonosis Parasitarias, Departamento de Biologia, Facultad de Ciencias Exactas y Naturales, Universidad Nacional de Mar del Plata, Funes 3250 (7600) Mar del Plata, Pcia. de Buenos Aires, Argentina.

出版信息

Rev Argent Microbiol. 2009 Apr-Jun;41(2):105-11.

PMID:19623901
Abstract

Hydatidosis is a zoonosis produced by the metacestode Echinococcus spp. The aims of this research are: to contribute to the knowledge of pediatric hydatidosis in the south-east of Buenos Aires province, to study its evolution from 1993 to 2002 at the Regional Maternity and Pediatric Hospital "Dr. Victorio Tetamanti", to determine the strains involved and to discuss the importance of the disease. The clinical records of diagnosed and/or operated patients were reviewed with regard to the hydatid disease. The strain was determined by using PCRs with Eg1 121a/122a primers. Forty-four cases were analyzed. Fifty nine point one per cent of the patients were boys. The mean age was 8 SD=3.8 years. Sixty one point four per cent had urban residence. Ultrasonography was used in 61% of the cases. The hepatic location was most frequently seen and the liver/lung ratio was 1.25. Ninety point nine per cent of patients received surgical treatment. Albendazole was used in 52% of cases. The average hospitalization time was 11 days. The G1/G2 strain group was determined. This report is the first one of its kind in the studied region. The permanence of hydatidosis in the region depends on the natural transmission of the parasite in the absence of control and prevention measures. The health authorities should implement strategies of prevention and control in the study area.

摘要

包虫病是由棘球绦虫的中绦期幼虫引起的一种人畜共患病。本研究的目的是:增进对布宜诺斯艾利斯省东南部儿童包虫病的了解,研究1993年至2002年期间在“维克托里奥·特塔曼蒂医生”地区妇产儿童医院该病的发展情况,确定所涉及的菌株并探讨该疾病的重要性。对确诊和/或接受手术治疗的包虫病患者的临床记录进行了回顾。通过使用Eg1 121a/122a引物进行聚合酶链反应来确定菌株。分析了44例病例。59.1%的患者为男性。平均年龄为8岁(标准差=3.8岁)。61.4%的患者居住在城市。61%的病例使用了超声检查。肝脏部位最为常见,肝/肺比例为1.25。90.9%的患者接受了手术治疗。52%的病例使用了阿苯达唑。平均住院时间为11天。确定了G1/G2菌株组。本报告是该研究地区此类报告中的首例。在缺乏控制和预防措施的情况下,该地区包虫病的持续存在取决于寄生虫的自然传播。卫生当局应在研究区域实施预防和控制策略。

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