Tveit Julie Victoria Holm, Saastad Eli, Stray-Pedersen Babill, Børdahl Per E, Flenady Vicki, Fretts Ruth, Frøen J Frederik
Division of Obstetrics and Gynecology, and Centre for Perinatal Research, Rikshospitalet University Hospital, University of Oslo, Medical Faculty, Norway.
BMC Pregnancy Childbirth. 2009 Jul 22;9:32. doi: 10.1186/1471-2393-9-32.
Women experiencing decreased fetal movements (DFM) are at increased risk of adverse outcomes, including stillbirth. Fourteen delivery units in Norway registered all cases of DFM in a population-based quality assessment. We found that information to women and management of DFM varied significantly between hospitals. We intended to examine two cohorts of women with DFM before and during two consensus-based interventions aiming to improve care through: 1) written information to women about fetal activity and DFM, including an invitation to monitor fetal movements, 2) guidelines for management of DFM for health-care professionals.
All singleton third trimester pregnancies presenting with a perception of DFM were registered, and outcomes collected independently at all 14 hospitals. The quality assessment period included April 2005 through October 2005, and the two interventions were implemented from November 2005 through March 2007. The baseline versus intervention cohorts included: 19,407 versus 46,143 births and 1215 versus 3038 women with DFM, respectively.
Reports of DFM did not increase during the intervention. The stillbirth rate among women with DFM fell during the intervention: 4.2% vs. 2.4%, (OR 0.51 95% CI 0.32-0.81), and 3.0/1000 versus 2.0/1000 in the overall study population (OR 0.67 95% CI 0.48-0.93). There was no increase in the rates of preterm births, fetal growth restriction, transfers to neonatal care or severe neonatal depression among women with DFM during the intervention. The use of ultrasound in management increased, while additional follow up visits and admissions for induction were reduced.
Improved management of DFM and uniform information to women is associated with fewer stillbirths.
感觉到胎动减少(DFM)的女性出现不良结局的风险增加,包括死产。挪威的14个分娩单位在一项基于人群的质量评估中记录了所有胎动减少的病例。我们发现,不同医院向女性提供的信息以及对胎动减少的处理方式差异很大。我们打算在两项基于共识的干预措施实施之前和期间,对两组有胎动减少情况的女性进行研究,这些干预措施旨在通过以下方式改善护理:1)向女性提供关于胎动和胎动减少的书面信息,包括邀请她们监测胎动;2)为医护人员制定胎动减少的管理指南。
记录所有在孕晚期感觉到胎动减少的单胎妊娠情况,并在所有14家医院独立收集结局数据。质量评估期为2005年4月至2005年10月,两项干预措施于2005年11月至2007年3月实施。基线组与干预组分别包括:19407例与46143例分娩,以及1215例与3038例有胎动减少情况的女性。
在干预期间,胎动减少的报告并未增加。有胎动减少情况的女性的死产率在干预期间有所下降:从4.2%降至2.4%,(比值比0.51,95%置信区间0.32 - 0.81),在整个研究人群中,从3.0/1000降至2.0/1000(比值比0.67,95%置信区间0.48 - 0.93)。在干预期间,有胎动减少情况的女性的早产、胎儿生长受限、转入新生儿护理或严重新生儿抑郁的发生率没有增加。管理中超声的使用增加,而额外的随访就诊和引产住院次数减少。
改善胎动减少的管理并向女性提供统一信息与减少死产有关。