Barahona M J, Vinagre I, Sojo L, Cubero J M, Pérez Antonio
Department of Endocrinology, Hospital Sant Pau, S. Antoni M. Claret 167, 08025 Barcelona, Spain.
Clin Med Res. 2009 Sep;7(3):96-8. doi: 10.3121/cmr.2009.816. Epub 2009 Jul 22.
We describe a 37-year-old man with a 4-month history of episodic muscular weakness, involving mainly lower-limbs. Hypokalemia was documented in one episode and managed with intravenous potassium chloride. Hyperthyroidism was diagnosed 4 months after onset of attacks because of mild symptoms. The patient was subsequently diagnosed as having thyrotoxic periodic paralysis associated with Graves' disease. Treatment with propranolol and methimazol was initiated and one year later he remains euthyroid and symptom free. Thyrotoxic periodic paralysis is a rare disorder, especially among Caucasians, but it should always be considered in patients with acute paralysis and hypokalemia, and thyroid function should be evaluated.
我们描述了一名37岁男性，有4个月发作性肌无力病史，主要累及下肢。一次发作时记录到低钾血症，通过静脉输注氯化钾进行处理。发作开始4个月后，因症状轻微诊断为甲状腺功能亢进症。该患者随后被诊断为与格雷夫斯病相关的甲状腺毒症性周期性瘫痪。开始使用普萘洛尔和甲巯咪唑治疗，一年后他甲状腺功能正常且无症状。甲状腺毒症性周期性瘫痪是一种罕见疾病，尤其在白种人中，但对于急性瘫痪和低钾血症患者应始终予以考虑，并评估甲状腺功能。
