WASP and SCAR/WAVE proteins: the drivers of actin assembly.
作者信息
Pollitt Alice Y, Insall Robert H
机构信息
Centre for Cardiovascular Sciences, Institute of Biomedical Research, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.
出版信息
J Cell Sci. 2009 Aug 1;122(Pt 15):2575-8. doi: 10.1242/jcs.023879.
Abstract
摘要
相似文献
1
WASP and SCAR/WAVE proteins: the drivers of actin assembly.WASP和SCAR/WAVE蛋白：肌动蛋白组装的驱动因子。
J Cell Sci. 2009 Aug 1;122(Pt 15):2575-8. doi: 10.1242/jcs.023879.
2
Actin binding to the central domain of WASP/Scar proteins plays a critical role in the activation of the Arp2/3 complex.肌动蛋白与WASP/Scar蛋白的中央结构域结合在Arp2/3复合物的激活中起关键作用。
J Biol Chem. 2006 Apr 14;281(15):10589-97. doi: 10.1074/jbc.M507470200. Epub 2005 Dec 23.
3
Regulation of actin dynamics by WASP family proteins.WASP家族蛋白对肌动蛋白动力学的调控。
J Biochem. 2003 Sep;134(3):309-13. doi: 10.1093/jb/mvg146.
4
Scar1 and the related Wiskott-Aldrich syndrome protein, WASP, regulate the actin cytoskeleton through the Arp2/3 complex.Scar1及相关的威斯科特-奥尔德里奇综合征蛋白（WASP）通过Arp2/3复合体调节肌动蛋白细胞骨架。
Curr Biol. 1998;8(25):1347-56. doi: 10.1016/s0960-9822(98)00015-3.
5
Hierarchical regulation of WASP/WAVE proteins.WASP/WAVE蛋白的分级调控
Mol Cell. 2008 Nov 7;32(3):426-38. doi: 10.1016/j.molcel.2008.10.012.
6
Regulation of actin dynamics by WASP and WAVE family proteins.WASP和WAVE家族蛋白对肌动蛋白动力学的调控
Trends Cell Biol. 2004 Jun;14(6):303-11. doi: 10.1016/j.tcb.2004.04.007.
7
A complex of Wiskott-Aldrich syndrome protein with mammalian verprolins plays an important role in monocyte chemotaxis.威斯科特-奥尔德里奇综合征蛋白与哺乳动物维普洛林形成的复合物在单核细胞趋化中起重要作用。
J Immunol. 2006 Jun 1;176(11):6576-85. doi: 10.4049/jimmunol.176.11.6576.
8
WASP and SCAR are evolutionarily conserved in actin-filled pseudopod-based motility.WASP和SCAR在基于肌动蛋白填充伪足的运动中在进化上是保守的。
J Cell Biol. 2017 Jun 5;216(6):1673-1688. doi: 10.1083/jcb.201701074. Epub 2017 May 4.
9
T-cell receptor ligation causes Wiskott-Aldrich syndrome protein degradation and F-actin assembly downregulation.T 细胞受体的交联导致 Wiskott-Aldrich 综合征蛋白的降解和 F-肌动蛋白组装的下调。
J Allergy Clin Immunol. 2013 Sep;132(3):648-655.e1. doi: 10.1016/j.jaci.2013.03.046. Epub 2013 May 16.
10
Differential regulation of WASP and N-WASP by Cdc42, Rac1, Nck, and PI(4,5)P2.Cdc42、Rac1、Nck和PI(4,5)P2对WASP和N-WASP的差异调节
Biochemistry. 2007 Mar 20;46(11):3494-502. doi: 10.1021/bi062152y. Epub 2007 Feb 16.
引用本文的文献
1
Signaling and actin waves at a glance.信号传导与肌动蛋白波概述。
J Cell Sci. 2025 Aug 15;138(16). doi: 10.1242/jcs.263634. Epub 2025 Aug 22.
2
Migratory responses in enucleated cells: The forces driving the locomotion movement of unicellular organisms.去核细胞中的迁移反应：驱动单细胞生物移动运动的力量。
PNAS Nexus. 2025 Jul 25;4(8):pgaf232. doi: 10.1093/pnasnexus/pgaf232. eCollection 2025 Aug.
3
Functional divergence of plant SCAR/WAVE proteins is determined by intrinsically disordered regions.植物SCAR/WAVE蛋白的功能差异由内在无序区域决定。
Sci Adv. 2025 May 23;11(21):eadt6107. doi: 10.1126/sciadv.adt6107. Epub 2025 May 21.
4
The WASP/WAVE Protein Family in Breast Cancer and Their Role in the Metastatic Cascade.乳腺癌中的WASP/WAVE蛋白家族及其在转移级联反应中的作用。
Cancer Genomics Proteomics. 2025 Mar-Apr;22(2):166-187. doi: 10.21873/cgp.20495.
5
ELK3-CYFIP2 axis-mediated actin remodeling modulates metastasis and natural killer cell responses in triple-negative breast cancer.ELK3-CYFIP2轴介导的肌动蛋白重塑调节三阴性乳腺癌中的转移和自然杀伤细胞反应。
J Exp Clin Cancer Res. 2025 Feb 10;44(1):48. doi: 10.1186/s13046-025-03309-7.
6
Role of WAVE3 as an actin binding protein in the pathology of triple negative breast cancer.波形肌动蛋白3作为一种肌动蛋白结合蛋白在三阴性乳腺癌病理中的作用
Cytoskeleton (Hoboken). 2025 Mar;82(3):130-144. doi: 10.1002/cm.21898. Epub 2024 Jul 18.
7
Shaping Drosophila eggs: unveiling the roles of Arpc1 and cpb in morphogenesis.塑造果蝇卵子：揭示 Arpc1 和 cpb 在形态发生中的作用。
Funct Integr Genomics. 2024 Jul 4;24(4):120. doi: 10.1007/s10142-024-01396-x.
8
A first-in-class Wiskott-Aldrich syndrome protein activator with antitumor activity in hematologic cancers.一种新型的威特综合征相关蛋白激活剂，具有血液系统恶性肿瘤的抗肿瘤活性。
Haematologica. 2024 Nov 1;109(11):3602-3614. doi: 10.3324/haematol.2022.282672.
9
Systemic cellular migration: The forces driving the directed locomotion movement of cells.全身细胞迁移：驱动细胞定向移动的力量。
PNAS Nexus. 2024 Apr 20;3(5):pgae171. doi: 10.1093/pnasnexus/pgae171. eCollection 2024 May.
10
Disulfidptosis decoded: a journey through cell death mysteries, regulatory networks, disease paradigms and future directions.二硫化物诱导的细胞死亡解析：探索细胞死亡之谜、调控网络、疾病模式及未来方向之旅
Biomark Res. 2024 Apr 29;12(1):45. doi: 10.1186/s40364-024-00593-x.
本文引用的文献
1
The WAVE regulatory complex is inhibited.WAVE调节复合体被抑制。
Nat Struct Mol Biol. 2009 May;16(5):561-3. doi: 10.1038/nsmb.1587. Epub 2009 Apr 12.
2
p53-cofactor JMY is a multifunctional actin nucleation factor.p53辅助因子JMY是一种多功能肌动蛋白成核因子。
Nat Cell Biol. 2009 Apr;11(4):451-9. doi: 10.1038/ncb1852. Epub 2009 Mar 15.
3
Analysis of WASp function during the wound inflammatory response--live-imaging studies in zebrafish larvae.斑马鱼幼体伤口炎症反应期间WASp功能的分析——活体成像研究
J Cell Sci. 2008 Oct 1;121(Pt 19):3196-206. doi: 10.1242/jcs.032235. Epub 2008 Sep 9.
4
Structural mechanism of WASP activation by the enterohaemorrhagic E. coli effector EspF(U).肠出血性大肠杆菌效应蛋白EspF(U)激活WASP的结构机制。
Nature. 2008 Aug 21;454(7207):1009-13. doi: 10.1038/nature07160. Epub 2008 Jul 23.
5
The pathogen protein EspF(U) hijacks actin polymerization using mimicry and multivalency.病原体蛋白EspF(U)通过模拟和多价性劫持肌动蛋白聚合。
Nature. 2008 Aug 21;454(7207):1005-8. doi: 10.1038/nature07170. Epub 2008 Jul 23.
6
WHAMM is an Arp2/3 complex activator that binds microtubules and functions in ER to Golgi transport.WHAMM是一种与微管结合并在从内质网到高尔基体的转运过程中发挥作用的Arp2/3复合物激活剂。
Cell. 2008 Jul 11;134(1):148-61. doi: 10.1016/j.cell.2008.05.032.
7
X-ray scattering study of activated Arp2/3 complex with bound actin-WCA.结合肌动蛋白-WCA的活化Arp2/3复合物的X射线散射研究。
Structure. 2008 May;16(5):695-704. doi: 10.1016/j.str.2008.02.013.
8
Arabidopsis SCARs function interchangeably to meet actin-related protein 2/3 activation thresholds during morphogenesis.拟南芥的SCAR蛋白在形态发生过程中可相互替换发挥作用，以达到肌动蛋白相关蛋白2/3的激活阈值。
Plant Cell. 2008 Apr;20(4):995-1011. doi: 10.1105/tpc.107.055350. Epub 2008 Apr 18.
9
Abi mutants in Dictyostelium reveal specific roles for the SCAR/WAVE complex in cytokinesis.盘基网柄菌中的Abi突变体揭示了SCAR/WAVE复合体在胞质分裂中的特定作用。
Curr Biol. 2008 Feb 12;18(3):203-10. doi: 10.1016/j.cub.2008.01.026.
10
Human subtelomeric WASH genes encode a new subclass of the WASP family.人类亚端粒WASH基因编码WASP家族的一个新亚类。
PLoS Genet. 2007 Dec;3(12):e237. doi: 10.1371/journal.pgen.0030237.
Zotero 插件