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视网膜血管阻塞:一个跨学科的挑战。

Retinal vascular occlusions: an interdisciplinary challenge.

机构信息

Klinikum Ludwigshafen, Augenklinik, Bremserstrasse 79, Ludwigshafen, Germany.

出版信息

Dtsch Arztebl Int. 2008 Jun;105(26):474-9. doi: 10.3238/arztebl.2008.0474. Epub 2008 Jun 27.

Abstract

INTRODUCTION

Retinal venous and arterial occlusions are common causes of visual loss. Depending on the location and extent, symptoms may vary from very discrete impairments to complete loss of sight.

METHODS

Selective literature review including the authors' own research data with a particular focus on interdisciplinary aspects.

RESULTS

Retinal vascular occlusions are not a uniform entity. Rather, they reflect the whole breadth of vascular disease. In arterial occlusion, embolic phenomena and Horton's arteritis should be excluded, in addition to local ophthalmological investigations. In retinal venous occlusion, optimal treatment of arterial hypertension is universally useful, while investigations for thrombophilia are useful in patients under 50 years of age. The results of intravitreal injection of corticosteroids and vascular endothelial growth factor inhibitors appear encouraging in treatment of macular edema secondary to retinal vein occlusion.

DISCUSSION

While local diagnostic and therapeutic measures are performed by ophthalmologists, there is an important role for interdisciplinary cooperation in the investigation and systemic treatment of these events.

摘要

简介

视网膜静脉和动脉阻塞是视力丧失的常见原因。根据位置和范围的不同,症状可能从非常离散的损伤到完全失明不等。

方法

包括作者自己的研究数据在内的选择性文献综述,特别关注跨学科方面。

结果

视网膜血管阻塞不是一个统一的实体。相反,它们反映了血管疾病的全貌。在动脉阻塞中,除了局部眼科检查外,还应排除栓塞现象和 Horton 动脉炎。在视网膜静脉阻塞中,动脉高血压的最佳治疗对所有人都有用,而对于 50 岁以下的患者,血栓形成倾向的检查是有用的。玻璃体内注射皮质类固醇和血管内皮生长因子抑制剂治疗视网膜静脉阻塞引起的黄斑水肿的结果令人鼓舞。

讨论

虽然眼科医生进行局部诊断和治疗措施,但在这些疾病的调查和系统治疗方面,跨学科合作具有重要作用。

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