Ramírez V, González A, de la Rosa E, González M, Rivera I, Hernández C, Ponce de León S
Universidad Autónoma Metropolitana-Xochimilco, Mexico, D.F.
J Oral Pathol Med. 1990 Nov;19(10):482-5. doi: 10.1111/j.1600-0714.1990.tb00791.x.
One hundred and twenty-five HIV-infected patients, of whom 49 (39%) were at early stages of the infection (CDC-II & III) and 76 (61%) in CDC IV, were prospectively examined. In 100 (80%) one or more oral mucosal lesions were observed; candidiasis (51%) and hairy leukoplakia (43%) were the commonest. Erythematous candidiasis was more often seen (35%) than the pseudomembranous type (16%), and appeared with the higher values at early than later stages. The prevalence of hairy leukoplakia, oral hyperpigmentation and xerostomia were incremented in groups CDC-IV. Pseudomembranous candidiasis and exfoliative cheilitis increased significantly with severity of disease. Our study demonstrates that oral alterations associated to HIV are a frequent finding, both at early (76%) and late (83%) stages of the infection in Mexican patients.
对125例HIV感染患者进行了前瞻性检查,其中49例(39%)处于感染早期(疾病控制中心II级和III级),76例(61%)处于疾病控制中心IV级。在100例(80%)患者中观察到一个或多个口腔黏膜病变;念珠菌病(51%)和毛状白斑(43%)最为常见。红斑型念珠菌病(35%)比假膜型(16%)更常见,且在早期比后期出现的比例更高。疾病控制中心IV级组中毛状白斑、口腔色素沉着和口干的患病率增加。假膜型念珠菌病和剥脱性唇炎随疾病严重程度显著增加。我们的研究表明,在墨西哥患者中,与HIV相关的口腔改变在感染早期(76%)和晚期(83%)都很常见。