Ramirez-Amador V, Esquivel-Pedraza L, Sierra-Madero J, Ponce-de-Leon S, Ponce-de-Leon S
Universidad Autonoma Metropolitana-Xochimilco, Mexico City, Mexico.
J Oral Pathol Med. 1998 Mar;27(3):135-40. doi: 10.1111/j.1600-0714.1998.tb01929.x.
A cross-sectional analysis was conducted in Mexico City from September 1989 to March 1996, to determine the prevalence of HIV-related oral manifestations by gender and route of HIV transmission. The diagnosis of HIV-associated oral lesions was based on preestablished criteria. For the statistical analysis chi-squared and Fisher's exact tests were used where appropriate. Odds ratios were calculated as estimates of the relative risks. Control of confounding factors was performed by logistic regression models. Oral lesions were present in 75% of 436 HIV+ patients. Hairy leukoplakia, erythematous and pseudomembranous candidosis, angular cheilitis and oral ulcers were frequently found. Patients who contracted HIV through blood transfusion were more likely to present erythematous candidosis (P=0.005) than subjects who acquired HIV through sexual transmission. Oral ulcers were seen only in men (P=0.02) and in individuals who contracted HIV through sexual transmission (P=0.02). This study brings valuable data in regard to differences in the type and prevalence of HIV-related oral lesions by gender and the risk categories analysed, particularly blood transfusion.
1989年9月至1996年3月在墨西哥城进行了一项横断面分析,以确定按性别和艾滋病毒传播途径划分的艾滋病毒相关口腔表现的患病率。艾滋病毒相关口腔病变的诊断基于既定标准。在适当情况下,使用卡方检验和费舍尔精确检验进行统计分析。计算比值比作为相对风险的估计值。通过逻辑回归模型控制混杂因素。436名艾滋病毒阳性患者中有75%存在口腔病变。经常发现毛状白斑、红斑和假膜性念珠菌病、口角炎和口腔溃疡。通过输血感染艾滋病毒的患者比通过性传播感染艾滋病毒的患者更易出现红斑性念珠菌病(P=0.005)。口腔溃疡仅见于男性(P=0.02)和通过性传播感染艾滋病毒的个体(P=0.02)。本研究提供了关于按性别和所分析的风险类别(特别是输血在内的风险类别划分的艾滋病毒相关口腔病变的类型和患病率差异的宝贵数据。