Almeida Jose, Mackay Edward, Javier Julian, Mauriello John, Raines Jeffrey
Miami Vein Center and University of Miami, FL, USA.
Vasc Endovascular Surg. 2009 Oct-Nov;43(5):467-72. doi: 10.1177/1538574409335916. Epub 2009 Jul 23.
The 2 primary objectives of this study were to investigate whether the 1470-nm wavelength can close a saphenous vein painlessly and determine safety, efficacy, and side effects of the 1470-nm laser. In all, 26 limbs were treated in the Dominican Republic, with a radially-emitting fiber at low energy ranging from 20 J/cm to 30 J/cm. Perivenous anesthesia was used selectively. Then 41 veins were treated with the 1470-nm laser at 30 J/cm at 5 watts, using standard perivenous tumescent anesthesia in Miami and compared to a historical control (980 nm, 80 J/cm, and 12 watts). We demonstrated that the 1470-nm wavelength endovenous laser system could not close saphenous veins without use of anesthesia. Closure with a dramatic reduction in energy when compared to a 980-nm wavelength control demonstrated a marked reduction in postoperative pain and ecchymosis; this implies that vein-wall perforations are minimized with this system.
本研究的两个主要目的是调查1470纳米波长能否无痛闭合大隐静脉，并确定1470纳米激光的安全性、有效性和副作用。在多米尼加共和国，共治疗了26条肢体，使用径向发射光纤，能量较低，范围为20焦耳/厘米至30焦耳/厘米。选择性地使用静脉周围麻醉。然后在迈阿密，使用标准的静脉周围肿胀麻醉，用1470纳米激光以30焦耳/厘米、5瓦的能量治疗41条静脉，并与历史对照组（980纳米、80焦耳/厘米和12瓦）进行比较。我们证明，1470纳米波长的静脉内激光系统在不使用麻醉的情况下无法闭合大隐静脉。与980纳米波长对照组相比，能量显著降低的闭合方式表明术后疼痛和瘀斑明显减少；这意味着该系统可将静脉壁穿孔降至最低。
