有机和无机防晒剂的体外紫外线A防护因子（PF-UVA）

In vitro UV-A protection factor (PF-UVA) of organic and inorganic sunscreens.

作者信息

Couteau C, El-Boury S, Paparis E, Sébille-Rivain V, Coiffard L J M

机构信息

Faculty of Pharmacy, Université de Nantes, Nantes Atlantique Universités, Nantes, France.

出版信息

Pharm Dev Technol. 2009;14(4):369-72. doi: 10.1080/10837450802683966.

DOI:10.1080/10837450802683966

PMID:19630696

Abstract

The objective of this research was to evaluate the efficacy of various sunscreen agents incorporated into an O/W emulsion. Within the scope of this study only an in vitro method was used. According to selected filter UVA, we can obtain more or less effective creams. With the seven available filters, we can cover a range of values between 2 and 12. In addition to these seven filters absorbing in UVA range, variously coated titanium dioxide and zinc oxide were tested as well. So it appears that the best organic UVA filter is anisotriazine at 10% (PF-UVA = 11.82). Its effectiveness is comparable with that of the titanium dioxide forms used at 25%. Photostability in Suntest showed that the more photostable UVA-filters are the benzophenones.

摘要

本研究的目的是评估添加到水包油乳液中的各种防晒剂的功效。在本研究范围内，仅使用了体外方法。根据所选的UVA滤光片，我们可以获得或多或少有效的乳膏。使用这七种可用的滤光片，我们可以覆盖2至12之间的一系列数值。除了这七种在UVA范围内吸收的滤光片外，还测试了各种包覆的二氧化钛和氧化锌。因此，似乎最佳的有机UVA滤光片是10%的异壬基三嗪（PF-UVA = 11.82）。其有效性与25%使用的二氧化钛形式相当。在Suntest中的光稳定性表明，光稳定性更高的UVA滤光片是二苯甲酮。