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[REACH注册研究对血管外科的意义]

[Implications of the REACH registry for vascular surgery].

作者信息

Alvarez-Fernández Luis Javier, Vallina-Victorero Vázquez Manuel Javier, Ramos Gallo María José, Santiago María Vicente

机构信息

Hospital de Cabueñes, Gijón, España.

出版信息

Med Clin (Barc). 2009 Sep;132 Suppl 2:25-9. doi: 10.1016/S0025-7753(09)71749-X.

Abstract

Because of the increase in life expectancy, peripheral artery disease (PAD) has become a major health problem. A study performed in Spain in persons aged more than 65 years old found an overall prevalence of PAD of 9.9%. The most important risk factors for PAD were smoking, diabetes mellitus, advanced age, hyperlipidemia and hypertension. Treatment includes smoking cessation, exercise, statins, platelet antiaggregants, cilostazol or hemorheologic agents, and revascularization techniques. Data from the Spanish arm of REACH indicate that the PAD subgroup shows the poorest control of blood pressure and cholesterol and that use of platelet antiaggregants and statins is lowest in these patients, indicating that therapeutic and preventive strategies are not being correctly applied.

摘要

由于预期寿命的增加,外周动脉疾病(PAD)已成为一个主要的健康问题。在西班牙对65岁以上人群进行的一项研究发现,PAD的总体患病率为9.9%。PAD最重要的危险因素是吸烟、糖尿病、高龄、高脂血症和高血压。治疗方法包括戒烟、运动、使用他汀类药物、血小板抗聚集剂、西洛他唑或血液流变学药物,以及血管重建技术。REACH研究西班牙部分的数据表明,PAD亚组的血压和胆固醇控制最差,这些患者使用血小板抗聚集剂和他汀类药物的比例最低,这表明治疗和预防策略未得到正确应用。

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