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[《化学品注册、评估、授权和限制制度》登记册对内科医学的影响]

[Implications of the REACH registry for internal medicine].

作者信息

Ramos Salado Juan Lucio

机构信息

Hospital Perpetuo Socorro, Complejo Hospitalario Universitario de Badajoz, España.

出版信息

Med Clin (Barc). 2009 Sep;132 Suppl 2:34-7. doi: 10.1016/S0025-7753(09)71751-8.

Abstract

Atherosclerotic cardiovascular disease continues to be the main cause of morbidity and mortality worldwide. Some of the essential characteristics of this disease are still unknown, even though many risk factors are well established. In addition, there are no exact data on the characteristics of patients at greatest risk of a new atherothrombotic episode. To fill these gaps, the Reduction of Atherothrombosis for Continued Health (REACH) registry has been established. The results of the REACH study confirm the need to understand atherothrombosis as a global disease and not to individualize it according to the diseased vascular bed. From the internist's point of view, the most interesting features are the following: the need for a multidisciplinary approach to the disease, with the participation of various medical and surgical specialties; due to their integrative perspective, internists should be a key figure in this team; the solution to this pandemic of cardiovascular mortality does not lie solely in the hands of health professionals but also requires the involvement of both public administrations and civil society.

摘要

动脉粥样硬化性心血管疾病仍然是全球发病和死亡的主要原因。尽管许多危险因素已明确,但该疾病的一些基本特征仍不清楚。此外,对于发生新的动脉粥样硬化血栓形成事件风险最高的患者特征,尚无确切数据。为填补这些空白,设立了“持续健康降低动脉粥样硬化血栓形成(REACH)注册研究”。REACH研究结果证实,有必要将动脉粥样硬化血栓形成视为一种全身性疾病,而不是根据病变血管床进行个体化判断。从内科医生的角度来看,最有意思的特点如下:该病需要多学科方法,有各种医学和外科专业的参与;由于内科医生具有综合视角,应成为该团队的关键人物;解决这一心血管死亡大流行问题不能仅靠卫生专业人员,还需要公共行政部门和民间社会的参与。

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