Roquer Jaume
Hospital del Mar-IMIM, Barcelona, España.
Med Clin (Barc). 2009 Sep;132 Suppl 2:30-3. doi: 10.1016/S0025-7753(09)71750-6.
Data from the REACH registry help to understand distinct problems affecting patients with arteriosclerotic disease. The arteriosclerotic burden evaluated by quantifying the number of diseased vascular territories is a marker of poor prognosis that increases the risk of recurrences, morbidity and mortality and death at 1 year. In cerebrovascular disease, it is important to highlight that patients with stroke are those with the highest rates of cerebral reinfarction and also show the highest combined rate of cardiovascular death or non-fatal myocardial infarction or stroke. Special care must be taken in patients who have had a transient ischemic attack since these patients accumulate a number of vascular risk factors. Data from the REACH registry suggest that preventive treatment and control of vascular risk factors could be improved, especially control of hypertension, diabetes and hypercholesterolemia. Consequently, preventive measures should be intensified in these patients to achieve adequate control of risk factors through encouraging healthy lifestyle habits, appropriate use of drugs and treatment adherence.
来自REACH注册研究的数据有助于了解影响动脉粥样硬化疾病患者的不同问题。通过量化病变血管区域数量评估的动脉粥样硬化负担是预后不良的一个指标，它会增加复发、发病和死亡风险以及1年内的死亡率。在脑血管疾病中，需要强调的是，中风患者是脑再梗死发生率最高的人群，同时也是心血管死亡、非致命性心肌梗死或中风综合发生率最高的人群。对于曾有过短暂性脑缺血发作的患者必须格外小心，因为这些患者积累了多种血管危险因素。REACH注册研究的数据表明，血管危险因素的预防性治疗和控制可以得到改善，尤其是高血压、糖尿病和高胆固醇血症的控制。因此，应加强对这些患者的预防措施，通过鼓励健康的生活习惯、合理用药和坚持治疗来实现对危险因素的充分控制。
