Angelini Paola, Kavadas Fotini, Sharma Navneet, Richardson Susan E, Tipples Graham, Roifman Chaim, Dror Yigal, Nofech-Mozes Yehuda
Division of Haematology and Oncology, Hospital for Sick Children, Toronto, Canada.
Pediatr Infect Dis J. 2009 Aug;28(8):746-8. doi: 10.1097/INF.0b013e31819b6c1f.
Varicella zoster vaccine is a safe vaccine that is rarely associated with life-threatening complications. We describe an immunocompetent child who developed transient severe aplastic anemia concomitant with a typical clinical and laboratory-proven chickenpox syndrome 3 weeks after immunization. A causative association between the vaccine and the hematologic disease is possible, and pediatricians should be aware of this severe although rare adverse event.
水痘带状疱疹疫苗是一种安全的疫苗，很少会引发危及生命的并发症。我们描述了一名免疫功能正常的儿童，在接种疫苗3周后出现了短暂的严重再生障碍性贫血，同时伴有典型的、经临床和实验室证实的水痘综合征。疫苗与血液疾病之间可能存在因果关联，儿科医生应该意识到这种严重但罕见的不良事件。
