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来自阿根廷胡椒(Schinus areira L.)和长叶胡椒(Schinus longifolia (Lindl.) Speg.)精油的乙酰胆碱酯酶抑制作用和抗氧化活性

Acetylcholinesterase inhibition and antioxidant activity of essential oils from Schinus areira L. and Schinus longifolia (Lindl.) Speg.

作者信息

Murray Ana P, Gurovic Maria S Vela, Rodriguez Silvana A, Murray María G, Ferrero Adriana A

机构信息

Departamento de Química, Universidad Nacional del Sur, Av. Alem 1253, B8000CPB Bahía Blanca, Argentina.

出版信息

Nat Prod Commun. 2009 Jun;4(6):873-6.

PMID:19634341
Abstract

The essential oils of Schinus areira L. and S. longifolia (Lindl.) Speg. (Anacardiaceae) have been studied for their in vitro anti-acetylcholinesterase and antioxidant activities. The chemical composition of the oils obtained by hydrodistillation was determined by GC-MS. Fruit and leaf oils of S. areira were analyzed separately. The essential oil from S. longifolia elicited marked enzymatic inhibition (IC50 = 20.0 +/- 1.0 microg/mL) and showed radical scavenger activity (IC50 = 25.2 +/- 2.4 microg/mL). The essential oil from S. areira leaves was more active than that of the fruits in both bioassays.

摘要

对秘鲁胡椒(Schinus areira L.)和长叶秘鲁胡椒(Schinus longifolia (Lindl.) Speg.)(漆树科)的精油进行了体外抗乙酰胆碱酯酶和抗氧化活性研究。通过气相色谱 - 质谱联用仪(GC - MS)测定了水蒸馏所得精油的化学成分。分别分析了秘鲁胡椒的果实油和叶油。长叶秘鲁胡椒的精油表现出显著的酶抑制作用(IC50 = 20.0 +/- 1.0微克/毫升),并显示出自由基清除活性(IC50 = 25.2 +/- 2.4微克/毫升)。在这两种生物测定中,秘鲁胡椒叶的精油比果实的精油活性更强。

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