Grant Jon E, Odlaug Brian L
Department of Psychiatry, University of Minnesota School of Medicine, 2450 Riverside Avenue, Minneapolis, MN 55454, USA.
Curr Psychiatry Rep. 2009 Aug;11(4):283-8. doi: 10.1007/s11920-009-0041-x.
Pathological skin picking (PSP) is a disabling disorder characterized by repetitive picking of the skin that causes tissue damage. Estimated to affect 2% to 5.4% of the population, PSP is currently listed as an impulse control disorder not otherwise specified. However, the repetitive and compulsive behaviors seen in PSP are phenomenologically and clinically similar to the behaviors seen in obsessive-compulsive disorder and other body-focused repetitive behaviors, such as trichotillomania and pathological nail biting. Animal neuroimaging research in related disorders such as obsessive-compulsive disorder and trichotillomania provides useful information for understanding PSP. Recent cognitive testing of individuals with PSP demonstrated impaired inhibitory control; these findings may assist in the proper characterization of PSP and aid in the development of effective treatment options. Although the disorder is common, appropriate treatments for PSP are limited. Pharmacotherapeutic and certain cognitive-behavioral interventions have demonstrated promise in treating this disorder and need to be explored further.
病理性皮肤搔抓(PSP)是一种致残性疾病,其特征是反复搔抓皮肤导致组织损伤。据估计,PSP影响2%至5.4%的人口,目前被列为未另行规定的冲动控制障碍。然而,PSP中出现的重复和强迫行为在现象学和临床上与强迫症及其他聚焦身体的重复行为(如拔毛癖和病理性咬甲症)中出现的行为相似。对强迫症和拔毛癖等相关疾病的动物神经影像学研究为理解PSP提供了有用信息。最近对PSP患者的认知测试表明其抑制控制受损;这些发现可能有助于对PSP进行恰当的特征描述,并有助于开发有效的治疗方案。尽管这种疾病很常见,但针对PSP的适当治疗方法有限。药物治疗和某些认知行为干预已显示出治疗这种疾病的前景,需要进一步探索。