University of Minnesota, Ambulatory Research Center, Department of Psychiatry, Minneapolis, USA.
Am J Drug Alcohol Abuse. 2010 Sep;36(5):296-303. doi: 10.3109/00952991003747543.
Pathologic skin picking (PSP) is characterized by the repetitive and compulsive picking of skin which results in tissue damage.
This article sought to examine the evidence supporting the phenomenological, and biological links between PSP and substance use disorders.
A review of the literature examining clinical presentation, comorbid psychiatric conditions, and treatment studies was used to examine the relationship of PSP and substance use disorders.
Prevalence rates of PSP range from 1.4-5.4% in the general population, with a much higher preponderance in females and in psychiatric patients. Significant medical complications are common, including scarring and infection. Although some pharmacologic agents (selective serotonin reuptake inhibitors, opioid antagonists, and glutamatergic agents) and non-pharmacologic treatments (habit-reversal therapy, Internet-based treatments, and acceptance-enhanced behavior therapy) have shown early promise in treating this often disabling disorder, evidence-based treatment options are still limited.
PSP shares several clinical similarities with substance use disorders including the failure to stop the behavior despite knowledge of the consequences and an associated pleasurable quality while engaging in the activity.
The consideration of some other impulse control disorders (e.g., pathological gambling) as addictions has helped advance treatment strategies. Conceptualizing PSP as an addiction, in some individuals, may lead to more effective treatment approaches.
病理性皮肤搔抓(PSP)的特征是反复的、强迫性的搔抓皮肤,导致组织损伤。
本文旨在探讨 PSP 与物质使用障碍在现象学和生物学方面的联系的证据。
对检查临床表型、合并精神疾病状况和治疗研究的文献进行了综述,以检查 PSP 和物质使用障碍之间的关系。
PSP 的患病率在普通人群中为 1.4-5.4%,女性和精神科患者的患病率更高。常见明显的医疗并发症,包括瘢痕和感染。虽然一些药物治疗(选择性 5-羟色胺再摄取抑制剂、阿片类拮抗剂和谷氨酸能药物)和非药物治疗(习惯逆转治疗、基于互联网的治疗和接受增强行为治疗)在治疗这种经常致残的疾病方面显示出了早期的希望,但仍缺乏基于证据的治疗选择。
PSP 与物质使用障碍有一些相似的临床特征,包括尽管知道后果,但仍无法停止这种行为,并且在进行活动时会产生愉悦的感觉。
将一些其他冲动控制障碍(如病理性赌博)视为成瘾,有助于推进治疗策略。将 PSP 概念化为某种成瘾,在某些个体中,可能会导致更有效的治疗方法。