Sheng Wang-Huei, Hung Chien-Ching, Huang Huai-Hsuan, Liang Shih-Yu, Cheng Yu-Jen, Ji Dar-Der, Chang Shan-Chwen
Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
Am J Trop Med Hyg. 2009 Aug;81(2):277-9.
We report the first case of granulomatous amebic encephalitis caused by Acanthamoeba in a previously healthy farmer in Taiwan who fell into a ditch. The DNA amplicons of amebas identified by polymerase chain reaction in the cerebrospinal fluid specimen and the ditch water specimens were identical and shared strong homology with A. castellanii . He survived after treatment with amphotericin B, rifampin, and corticosteroids.
我们报告了台湾首例由棘阿米巴引起的肉芽肿性阿米巴脑炎病例，患者为一名此前健康的农民，他掉进了一条沟渠。通过聚合酶链反应在脑脊液标本和沟渠水样中鉴定出的阿米巴DNA扩增子相同，且与卡氏棘阿米巴具有高度同源性。他在接受两性霉素B、利福平及皮质类固醇治疗后存活下来。
