Huang Haidong, Liu Yun, Liu Rulin
Key Laboratory of Molecular Microbiology Technology, Ministry of Education, College of Life Sciences, Nankai University, Tianjin 300071, China.
Wei Sheng Wu Xue Bao. 2009 May;49(5):560-6.
The genus Sphingomonas was established in 1990. Sphingomonas spp. synthesize sphingans, structurally related biopolymers such as gellan, welan and diutan. At present, only gellan is applied widely in foods and pharmaceuticals. The economic value of other sphingans has not been well explored, and related research of sphingans still remains limited. In the present review, we address the latest taxonomy developments of Sphingomonas, details about structure, characteristics and biosynthetic pathway of sphingans, current knowledge on the molecular genetics and genetic engineering of sphingans. In addition, we indicate future research needs.
鞘氨醇单胞菌属是1990年建立的。鞘氨醇单胞菌合成鞘脂聚糖，这是一类结构相关的生物聚合物，如结冷胶、韦兰胶和迪坦胶。目前，只有结冷胶在食品和制药领域有广泛应用。其他鞘脂聚糖的经济价值尚未得到充分探索，关于鞘脂聚糖的相关研究仍然有限。在本综述中，我们阐述了鞘氨醇单胞菌最新的分类学进展、鞘脂聚糖的结构、特性和生物合成途径的详细信息、目前关于鞘脂聚糖分子遗传学和基因工程的知识。此外，我们指出了未来的研究需求。
