Iliffe Steve, Kharicha Kalpa, Carmaciu Claudia, Harari Danielle, Swift Cameron, Gillman Gerhard, Stuck Andreas E
Department of Primary Care & Population Sciences, University College London, London, UK.
BMC Fam Pract. 2009 Jul 28;10:54. doi: 10.1186/1471-2296-10-54.
Pain and depression are known to be associated in later life, and both have a negative effect on physical performance both separately and in combination. The nature of the relationships between pain intensity and depression in elderly persons experiencing pain is less clear. The objectives of this study were to explore which factors are associated with depressed mood in older people experiencing pain, and to test the hypothesis that older people experiencing pain are at risk of depressed mood according to the severity or frequency of their pain. In addition we explored whether other potentially modifiable factors might increase the risk of depressed mood in these persons.
The study is a secondary analysis of baseline data for four hundred and six community-dwelling non-disabled people aged 65 and over registered with three group practices in suburban London who had experienced pain in the past 4 weeks. Intensity and frequency of pain was measured using 24 item Geriatric Pain Measure (GPM) and the presence of depressive symptoms using the 5 item Mental Health Inventory. Risk for social isolation was measured using the 6 item Lubben Social Network scale and instrumental activities of daily living (IADL) were also measured.
Overall 76 (19%) had depressed mood. Pain frequency and severity were not statistically significantly associated with depressed mood in this population. In multivariate analyses, significant predictors of the presence of depressive symptoms were difficulties with basic ADLs (OR 2.8, 95% CI 1.1.7.8), risk for social isolation (OR 4.1, 95% CI 1.8-9.3), and basic education only (OR 2.2, 95% CI 1.1-4.4).
Older people experiencing pain are also likely to experience depression. Among those experiencing pain, social network and functional status seem to be more important predictors of depressive symptoms than the severity of pain. Further studies should evaluate whether improvement of social network and functional status might reduce depressive symptoms in older patients.
已知疼痛与晚年的抑郁相关,且二者单独或共同对身体机能均有负面影响。在经历疼痛的老年人中,疼痛强度与抑郁之间关系的本质尚不清楚。本研究的目的是探讨哪些因素与经历疼痛的老年人的抑郁情绪相关,并检验这样一个假设,即经历疼痛的老年人会根据其疼痛的严重程度或频率而有抑郁情绪的风险。此外,我们还探讨了其他潜在的可改变因素是否可能增加这些人抑郁情绪的风险。
本研究是对伦敦郊区三家团体诊所登记的406名65岁及以上社区居住的非残疾老人的基线数据进行的二次分析,这些老人在过去4周内经历过疼痛。使用24项老年疼痛量表(GPM)测量疼痛的强度和频率,使用5项心理健康量表测量抑郁症状的存在情况。使用6项鲁本社交网络量表测量社会隔离风险,并测量日常生活工具性活动(IADL)。
总体而言,76人(19%)有抑郁情绪。在该人群中,疼痛频率和严重程度与抑郁情绪无统计学显著关联。在多变量分析中,抑郁症状存在的显著预测因素是基本日常生活活动困难(比值比[OR]2.8,95%置信区间[CI]1.1 - 7.8)、社会隔离风险(OR 4.1,95%CI 1.8 - 9.3)以及仅接受过基础教育(OR 2.2,95%CI 1.1 - 4.4)。
经历疼痛的老年人也可能经历抑郁。在那些经历疼痛的人中,社交网络和功能状态似乎比疼痛严重程度更重要的抑郁症状预测因素。进一步的研究应评估改善社交网络和功能状态是否可能减轻老年患者的抑郁症状。