[Biochemical markers of bone turnover. New aspect. Bone metabolism movement in various sports and physical activities].

It is generally known that bone mineral density increases when we perform sports and physical activities. However, bone metabolism movement varies depending not only on the type, frequency and intensity of sport and physical activity, but also on age and sex. Regarding for the bone metabolism movement showing a high power exercise, it is assumed that increase of bone mineral density occurs by bone formation being promoted. On the other hand, it is reported that bone mineral density of endurance athletes such as marathon runners is lower than that of non-athletes. In the bone metabolism movement of endurance exercises, bone resorption is temporarily promoted after the exercise, followed by the promotion of bone formation. Type I collagen cross-linked N-telopeptides (NTX) have a potential to be markers for early diagnosis of stress fracture.