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本文引用的文献

1
Molecular predictors in the early diagnosis of oral cancer.口腔癌早期诊断中的分子预测指标
J Clin Diagn Res. 2013 May;7(5):942-4. doi: 10.7860/JCDR/2013/5058.2983. Epub 2013 Mar 21.
2
The role of direct visual fluorescent examination (VELscope) in routine screening for potentially malignant oral mucosal lesions.直接目视荧光检查（VELscope）在常规筛查潜在恶性口腔黏膜病变中的作用。
Oral Surg Oral Med Oral Pathol Oral Radiol. 2012 Nov;114(5):636-43. doi: 10.1016/j.oooo.2012.07.484.
3
Use of fluorescent light in detecting malignant and premalignant lesions in the oral cavity: a prospective, single-blind study.荧光灯在口腔恶性和癌前病变检测中的应用：一项前瞻性、单盲研究。
J Otolaryngol Head Neck Surg. 2012 Jun 1;41(3):164-8.
4
[Detection of potentially malignant and malignant lesions of oral cavity using autofluorescence visualization device].[使用自体荧光可视化设备检测口腔潜在恶性和恶性病变]
Kokubyo Gakkai Zasshi. 2011 Jun;78(2):73-80.
5
Efficacy of tissue autofluorescence imaging (VELScope) in the visualization of oral mucosal lesions.组织自体荧光成像（VELScope）在口腔黏膜病变可视化中的疗效。
Head Neck. 2012 Jun;34(6):856-62. doi: 10.1002/hed.21834. Epub 2011 Aug 4.
6
Autofluorescence imaging of potentially malignant mucosa lesions.潜在恶性黏膜病变的自体荧光成像
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2011 May;111(5):568-77. doi: 10.1016/j.tripleo.2010.12.010. Epub 2011 Mar 22.
7
Evaluation of an autofluorescence based imaging system (VELscope™) in the detection of oral potentially malignant disorders and benign keratoses.基于自发荧光的成像系统（VELscope™）在口腔潜在恶性疾病和良性角化病检测中的评估。
Oral Oncol. 2011 Apr;47(4):274-7. doi: 10.1016/j.oraloncology.2011.02.001.
8
Effectiveness of autofluorescence to identify suspicious oral lesions--a prospective, blinded clinical trial.自发荧光识别可疑口腔病变的效果——一项前瞻性、盲法临床试验。
Clin Oral Investig. 2011 Dec;15(6):975-82. doi: 10.1007/s00784-010-0455-1. Epub 2010 Aug 17.
9
Advances in fluorescence imaging techniques to detect oral cancer and its precursors.荧光成像技术在口腔癌及其前体检测中的进展。
Future Oncol. 2010 Jul;6(7):1143-54. doi: 10.2217/fon.10.79.
10
Evaluation of a low-cost, portable imaging system for early detection of oral cancer.用于口腔癌早期检测的低成本便携式成像系统的评估
Head Neck Oncol. 2010 Apr 22;2:10. doi: 10.1186/1758-3284-2-10.

基于自体荧光的口腔癌诊断技术。

Autofluorescence based diagnostic techniques for oral cancer.

作者信息

Balasubramaniam A Murali, Sriraman Rajkumari, Sindhuja P, Mohideen Khadijah, Parameswar R Arjun, Muhamed Haris K T

机构信息

Department of Oral and Maxillofacial Pathology, Sathyabama University Dental College and Hospital, Chennai, Tamil Nadu, India.

Department of Oral Pathology and Microbiology, G.D. Karthik Clinic, Karaikudi, Tamil Nadu, India.

出版信息

J Pharm Bioallied Sci. 2015 Aug;7(Suppl 2):S374-7. doi: 10.4103/0975-7406.163456.

DOI:10.4103/0975-7406.163456
PMID:26538880
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4606622/
Abstract

Oral cancer is one of the most common cancers worldwide. Despite of various advancements in the treatment modalities, oral cancer mortalities are more, particularly in developing countries like India. This is mainly due to the delay in diagnosis of oral cancer. Delay in diagnosis greatly reduces prognosis of the treatment and also cause increased morbidity and mortality rates. Early diagnosis plays a key role in effective management of oral cancer. A rapid diagnostic technique can greatly aid in the early diagnosis of oral cancer. Now a day's many adjunctive oral cancer screening techniques are available for the early diagnosis of cancer. Among these, autofluorescence based diagnostic techniques are rapidly emerging as a powerful tool. These techniques are broadly discussed in this review.

摘要

口腔癌是全球最常见的癌症之一。尽管治疗方式有了各种进步，但口腔癌死亡率仍然较高，尤其是在印度等发展中国家。这主要是由于口腔癌诊断延迟。诊断延迟大大降低了治疗的预后，还导致发病率和死亡率上升。早期诊断在口腔癌的有效管理中起着关键作用。一种快速诊断技术可以极大地帮助口腔癌的早期诊断。如今，有许多辅助口腔癌筛查技术可用于癌症的早期诊断。其中，基于自体荧光的诊断技术正迅速成为一种强大的工具。本综述将对这些技术进行广泛讨论。