Melange M, Vanheuverzwyn R
Centre de Coloproctologie, Université Catholique de Louvain.
Acta Gastroenterol Belg. 1990 May-Jun;53(3):346-50.
The authors review the literature about the aetiopathogenesis, the epidemiology and the treatment of uncomplicated diverticular disease of the colon. The influence of dietary fibre deficiency explaining the increasing prevalence in industrialized countries and the variable geographical distribution are explained, as well as the effects of dietary fibres on colonic functions. Progressive elastosis of the taeniae may explain the influence of age on the incidence of diverticulosis. The rationale for the introduction of dietary fibre into the treatment is based on the observation that a high fibre diet such as coarse bran is lowering the colonic pressure and therefore may prevent the development of new diverticula and complications, although an effect on symptoms is not always obtained.
作者回顾了关于结肠单纯性憩室病的病因发病机制、流行病学及治疗的文献。解释了膳食纤维缺乏在工业化国家患病率上升及地理分布差异方面的影响,以及膳食纤维对结肠功能的作用。结肠带的进行性弹性组织变性可能解释了年龄对憩室病发病率的影响。将膳食纤维引入治疗的理论依据是基于这样的观察:高纤维饮食如粗麸皮可降低结肠压力,因此可能预防新憩室及并发症的发生,尽管对症状的影响并非总能实现。