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麸皮、卵叶车前草种子和乳果糖对憩室病结肠功能的比较。

Comparison of bran, ispaghula, and lactulose on colon function in diverticular disease.

作者信息

Eastwood M A, Smith A N, Brydon W G, Pritchard J

出版信息

Gut. 1978 Dec;19(12):1144-7. doi: 10.1136/gut.19.12.1144.

Abstract

Bran, ispaghula (Fybogel), and lactulose were given to three groups of patients with diverticular disease for four weeks. Faecal weights, bile acids, fat and electrolytes, transit time, and colonic motility were estimated before and after treatment. Stool weight increased, notably with Fybogel. Cereal bran had the greatest effect on the transit time, reducing it significantly. There were no changes in faecal bile acids, fat or electrolytes. Coarse bran reduced colonic motility and the number of high pressure waves after food; Fybogel increased the basal pressure and was without effect on the food-stimulated pressures; whereas lactulose influenced neither. All agents paradoxically equally alleviated symptoms.

摘要

将麸皮、卵叶车前(Fybogel)和乳果糖分别给予三组憩室病患者,持续四周。在治疗前后分别评估粪便重量、胆汁酸、脂肪和电解质、转运时间以及结肠动力。粪便重量增加,特别是服用Fybogel后。谷物麸皮对转运时间影响最大,使其显著缩短。粪便胆汁酸、脂肪或电解质无变化。粗麸皮降低结肠动力以及进食后高压波的数量;Fybogel增加基础压力,对食物刺激的压力无影响;而乳果糖对两者均无影响。所有药物均同样反常地缓解了症状。

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