Vlemmas I, Wohlsein P, Trautwein G, Kanakudis G, Tsangaris T
Institut für Pathologie der Tierärztlichen Fakultät Thessaloniki, Griechenland.
Berl Munch Tierarztl Wochenschr. 1990 Dec 1;103(12):422-5.
Formalin-fixed tissue samples obtained from puppies experimentally infected with canine parvovirus type 2 (CPV-2) were investigated immunohistologically with the direct immunoperoxidase method. Besides cardiac muscle and lymphatic tissues, bone marrow, intestine, liver, kidney, pancreas and to a lesser degree lung stained positive for viral antigen and are considered as sites of viral replication. The distribution of viral antigen reveals a tropism of CPV-2 to numerous organs in puppies infected during the first week of life.
