Mejzlíková E, Novák J, Adámková H
Ocní oddĕlení Pardubické krajské nemocnice, a. s., a Fakulta zdravotnických studií Univerzity Pardubice.
Cesk Slov Oftalmol. 2009 May;65(3):75-8.
Ischemic edema of the retina develops after CRAO and a regressive phase follows usually without any possibility of objectification. The aim of the study is to determine dynamics of edematous changes in the central retina using the OCT (Optical Coherence Tomography).
Department of Ophthalmology, Regional Hospital in Pardubice, Czech Republic, E.U.
During the period between June 2004 and January 2005, ten patients with the diagnosis of CRAO were examined by means of Stratus OCT3 (Zeiss). A protocol designed for analysis of the thickness and volume of the macula (Fast Macular Thickness Map) was used for the evaluation. Obtained readings were compared with the healthy eye. Examinations were performed on the 1st up to the 5th day after the CRAO onset and 2, 5, and 10 weeks thereafter.
The average volume of the macula (Average Total Macula Volume) of the affected eye was (mean +/- SD; mm3): at the day of diagnosis (the initial examination) 9.196 +/- 1.376 (range, 10.315-7.301), the 2nd week 7.313 +/- 1.209 (range, 9.441-5.854), the 5th week 5.970 +/- 0.688 (range, 7.401-4.971), and the 10th week 5.091 +/- 0.558 (range, 5.768-3.989). The average volume of the most swollen macular quadrate was (mean +/- SD; mm3): at the day of diagnosis (the initial examination) 0.695 +/- 0.319 (range, 1.526-0.359), the 2nd week 0.607 +/- 0.206 (range, 1.118-0.416), the 5th week 0.520 +/- 0.220 (range, 1.070-0.334), and the 10th week 0.409 +/- 0.195 (range 0.948-0.282). In some patients, the onset of macular atrophy was found 5 weeks after the CRAO. No edema in the macular area was confirmed in any patient 10 weeks after the CRAO.
On the average, we proved the regression phase of the retinal edema 5 weeks after the CRAO appearance. The OCT examination appears to be a suitable method for the determination of the dynamics of the edematous changes in the macular area after the CRAO.
视网膜中央动脉阻塞（CRAO）后会出现视网膜缺血性水肿，随后通常进入消退期，且一般无法客观化评估。本研究旨在利用光学相干断层扫描（OCT）确定视网膜中央区水肿变化的动态过程。
欧盟捷克共和国帕尔杜比采地区医院眼科
在2004年6月至2005年1月期间，对10例诊断为CRAO的患者采用Stratus OCT3（蔡司公司）进行检查。使用专门设计的用于分析黄斑厚度和体积的方案（快速黄斑厚度图）进行评估。将获得的数据与健眼进行比较。在CRAO发病后的第1天至第5天以及此后的第2、5和10周进行检查。
患眼黄斑的平均体积（平均总黄斑体积，单位：mm³）为：诊断当天（初次检查）9.196±1.376（范围10.315 - 7.301），第2周7.313±1.209（范围9.441 - 5.854），第5周5.970±0.688（范围7.401 - 4.971），第10周5.091±0.558（范围5.768 - 3.989）。最肿胀黄斑象限的平均体积（单位：mm³）为：诊断当天（初次检查）0.695±0.319（范围1.526 - 0.359），第2周0.607±0.206（范围1.118 - 0.416），第5周0.520±0.220（范围1.070 - 0.334），第10周0.409±0.195（范围0.948 - 0.282）。部分患者在CRAO发病5周后出现黄斑萎缩。在CRAO发病10周后，未在任何患者中确认黄斑区存在水肿。
平均而言，我们证实了CRAO出现5周后视网膜水肿进入消退期。OCT检查似乎是确定CRAO后黄斑区水肿变化动态的合适方法。
