Department of Ophthalmology, Changhua Christian Hospital, Changhua, Taiwan.
Retina. 2011 Apr;31(4):730-7. doi: 10.1097/IAE.0b013e3181f2a15c.
To evaluate the structural features of central retinal artery occlusion by means of optical coherence tomography.
Eleven consecutive patients with acute central retinal artery occlusion and at least 3-month follow-up were enrolled prospectively in this study. The main outcome measures included best-corrected visual acuity, foveal thickness (FT), and total macular volume by optical coherence tomography.
Five male and six female patients with central retinal artery occlusion were examined. The mean age was 71.2 ± 8.7 years (range, 59-83 years). Mean FT and total macular volume were 195 ± 26 μm and 6.41 ± 0.33 mm, respectively, in normal fellow eyes, increased to 299 ± 76 μm and 7.90 ± 0.93 mm, respectively, at initial examination and declined to 167 ± 30 μm and 4.85 ± 0.68 mm, respectively, at 3-month follow-up. Mean reduction in FT was 181 ± 61 μm (range, 120-270 μm) in eyes with poor visual outcome and 43 ± 25 μm (range, 15-74 μm) in eyes with fair visual outcome. Statistical analysis revealed that the relationships among visual prognosis and initial FT and initial total macular volume were not significant.
Optical coherence tomography provides special information about central retinal artery occlusion. There were marked and variable changes in FT and total macular volume. Limited reduction in macular thickness might indicate a fair visual outcome.
通过光学相干断层扫描评估视网膜中央动脉阻塞的结构特征。
本研究前瞻性纳入 11 例急性视网膜中央动脉阻塞患者，均至少随访 3 个月。主要观察指标包括最佳矫正视力、光学相干断层扫描的中心凹厚度（FT）和全黄斑体积。
纳入 5 例男性和 6 例女性视网膜中央动脉阻塞患者，平均年龄 71.2±8.7 岁（5983 岁）。正常对侧眼的平均 FT 和全黄斑体积分别为 195±26μm 和 6.41±0.33mm，初始检查时增加至 299±76μm 和 7.90±0.93mm，3 个月随访时分别降至 167±30μm 和 4.85±0.68mm。视力预后较差眼的 FT 平均减少 181±61μm（范围 120270μm），视力预后尚可眼的 FT 平均减少 43±25μm（范围 15~74μm）。统计学分析显示，视力预后与初始 FT 和初始全黄斑体积之间的关系无统计学意义。
光学相干断层扫描可为视网膜中央动脉阻塞提供特殊信息。FT 和全黄斑体积有明显且可变的变化。黄斑厚度的有限减少可能预示着尚可的视力预后。
