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大肠杆菌中甘露醇(mtl)操纵子的校正序列。

Corrected sequence of the mannitol (mtl) operon in Escherichia coli.

作者信息

Jiang W, Wu L F, Tomich J, Saier M H, Niehaus W G

机构信息

Department of Biochemistry and Nutrition, Virginia Polytechnic Institute and State University, Blacksburg 24061-0308.

出版信息

Mol Microbiol. 1990 Nov;4(11):2003-6. doi: 10.1111/j.1365-2958.1990.tb02050.x.

Abstract

The previously published sequences of the operator-promoter region of the mannitol operon of Escherichia coli and of the mtlD gene have been found to contain a number of errors. The major conclusions reported previously were correct, but additionally it is now clear that a C-terminal portion of mannitol-1-phosphate dehydrogenase (the mtlD gene product) exhibits significant sequence identity with an amino-terminal region of human liver fructose-6-phosphate-2-kinase:fructose-2,6-bisphosphatase.

摘要

此前发表的大肠杆菌甘露醇操纵子的操纵子-启动子区域及mtlD基因的序列已发现存在一些错误。之前报道的主要结论是正确的,但现在还清楚地表明,甘露醇-1-磷酸脱氢酶(mtlD基因产物)的C端部分与人类肝脏果糖-6-磷酸-2-激酶:果糖-2,6-二磷酸酶的N端区域具有显著的序列同一性。

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