Department of Obstetrics & Gynaecology, The Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong S.A.R., China.
Ultrasound Obstet Gynecol. 2009 Aug;34(2):196-200. doi: 10.1002/uog.6442.
To quantify the three-dimensional (3D) ultrasound characteristics of ovaries in Chinese women with polycystic ovarian syndrome (PCOS) and to compare these with previous data on a Caucasian cohort with PCOS.
3D pelvic ultrasound was performed in 40 Chinese women with PCOS and 40 controls. Ovarian volume, stromal volume and echogenicity, and antral follicle count (AFC) were measured and ovarian blood flow was quantified using both 3D power Doppler and two-dimensional (2D) pulsed wave Doppler. These data were compared with previously published data on a Caucasian cohort with PCOS.
Compared with controls, women with PCOS had a higher AFC (median (range), 15 (11-30) vs. 5.5 (1-10) per ovary, P < 0.01), ovarian volume (12.32 (8.10-16.16) mL vs. 5.64 (2.62-8.81) mL, P < 0.01) and stromal volume (9.74 (6.44-13.56) mL vs. 4.07 (1.52-6.67) mL, P < 0.01) but were comparable in stromal echogenicity and ovarian blood flow as measured by 3D power Doppler or 2D pulsed wave Doppler indices. However, in comparison with a previously reported Caucasian cohort with PCOS, the ovaries of Chinese women with PCOS had a significantly smaller stromal volume (median (range), 9.74 (6.44-13.56) mL vs. 10.79 (5.65-17.12) mL, P < 0.05), were less echogenic as reflected in a lower mean gray value (22.43 (13.13-35.50) vs. 32.36 (19.35-53.71), P < 0.01), and had reduced ovarian blood flow as reflected in a lower flow index (30.19 (23.32-44.88) vs. 33.54 (21.88-51.65), P < 0.05).
Based on 3D ultrasound measurements, Chinese women with PCOS have an increased stromal volume compared with controls. However, their stromal volume, echogenicity and vascularity is significantly lower than that in Caucasian women with PCOS. The possible etiology for these differences is discussed.
定量分析中国多囊卵巢综合征（PCOS）患者的卵巢 3D 超声特征，并与之前报道的白种人 PCOS 患者数据进行比较。
对 40 例中国 PCOS 患者和 40 例对照者进行盆腔 3D 超声检查。测量卵巢体积、间质体积和回声强度以及窦卵泡计数（AFC），并使用 3D 能量多普勒和二维（2D）脉冲波多普勒评估卵巢血流。将这些数据与之前报道的白种人 PCOS 患者数据进行比较。
与对照组相比，PCOS 患者的 AFC（中位数（范围），15（11-30）个/卵巢 vs. 5.5（1-10）个/卵巢，P＜0.01）、卵巢体积（12.32（8.10-16.16）mL vs. 5.64（2.62-8.81）mL，P＜0.01）和间质体积（9.74（6.44-13.56）mL vs. 4.07（1.52-6.67）mL，P＜0.01）均较高，但 3D 能量多普勒或 2D 脉冲波多普勒指数评估的间质回声强度和卵巢血流无显著差异。然而，与之前报道的白种人 PCOS 患者相比，中国 PCOS 患者的卵巢间质体积较小（中位数（范围），9.74（6.44-13.56）mL vs. 10.79（5.65-17.12）mL，P＜0.05），平均灰度值较低（22.43（13.13-35.50）vs. 32.36（19.35-53.71），P＜0.01），血流指数较低（30.19（23.32-44.88）vs. 33.54（21.88-51.65），P＜0.05），提示卵巢血流减少。
基于 3D 超声测量，中国 PCOS 患者的间质体积与对照组相比增加，但间质体积、回声强度和血管密度显著低于白种人 PCOS 患者。讨论了这些差异的可能病因。
