Younesi Ladan, Safarpour Lima Zeinab, Akbari Sene Azadeh, Hosseini Jebelli Zahra, Amjad Ghazaleh
Shahid Akbarabadi Clinical Research Development Unit (ShACRDU), Iran University of Medical Sciences (IUMS), Tehran, Iran.
Department of Obstetrics and Gynecology, IVF Fellowship, Shahid Akbar-Abadi Hospital IVF Center, Iran University of Medical Sciences, Tehran, Iran.
Endocr Connect. 2019 Jan 1;8(1):50-56. doi: 10.1530/EC-18-0423.
Polycystic ovarian syndrome (PCOS) is one of the most common endocrine disorders. The aim of this study was to find the correlation between color Doppler ultrasound and serum tests as auxiliary diagnostic criteria in areas where there is no possibility of some tests. A total of 108 patients were enrolled. They were divided into three groups including patients with PCOS, patients with PCOA ultrasound, patients with ovaries and normal hormone tests. Transvaginal sonography was performed from three groups and the results were evaluated in gray scale. The volume of the ovary, the number of follicles and the placement of follicles were recorded using using Doppler spectrum of uterine artery and ovarian stroma. Their arterial resistance index was also calculated. In the next step, serum samples were evaluated to determine the level of LH, FSH, free testosterone, DHEAS and 17-OHP hormones in the early follicular phase. Gray scale ultrasonographic findings (volume and number of ovarian follicles) as well as LH values were higher in patients with PCOS than those in the other two groups. These results proved the reliability of using these factors in the prediction of PCOS. In this study, Doppler indexes did not correlate with the size of the ovaries, the number of ovarian follicles and the measured hormone levels. The findings of transvaginal ultrasound and investigating the relationship with clinical and laboratory outcomes, a more suitable pattern could be chosen for more accurate patient selection and, leading to timely treatment and reducing the complications of the disease.
多囊卵巢综合征(PCOS)是最常见的内分泌疾病之一。本研究的目的是在无法进行某些检查的地区,寻找彩色多普勒超声与血清检测作为辅助诊断标准之间的相关性。共纳入108例患者。他们被分为三组,包括多囊卵巢综合征患者、超声检查提示多囊卵巢形态(PCOA)患者以及卵巢和激素检测正常的患者。对三组患者进行经阴道超声检查,并以灰阶模式评估结果。使用子宫动脉和卵巢基质的多普勒频谱记录卵巢体积、卵泡数量和卵泡位置。还计算了它们的动脉阻力指数。下一步,评估血清样本以确定卵泡早期促黄体生成素(LH)、促卵泡生成素(FSH)、游离睾酮、硫酸脱氢表雄酮(DHEAS)和17-羟孕酮(17-OHP)激素的水平。多囊卵巢综合征患者的灰阶超声检查结果(卵巢卵泡体积和数量)以及LH值高于其他两组。这些结果证明了使用这些因素预测多囊卵巢综合征的可靠性。在本研究中,多普勒指数与卵巢大小、卵巢卵泡数量和所测激素水平无关。经阴道超声检查结果以及与临床和实验室结果的关系研究,可以选择更合适的模式,以便更准确地选择患者,从而实现及时治疗并减少疾病并发症。