Sahgal Arjun, Ma Lijun, Chang Eric, Shiu Almon, Larson David A, Laperriere Normand, Yin Fang-Fang, Tsao May, Menard Cynthia, Basran Parminder S, Létourneau Daniel, Heydarian Mostafa, Beachey David, Shukla Vershalee, Cusimano Michael, Hodaie Mojgan, Zadeh Gelareh, Bernstein Mark, Schwartz Michael
Department of Radiation Oncology, Sunnybrook Odette Cancer Centre, the Princess Margaret Hospital, and the Joey Toby Tanenbaum family Gamma Knife Center, University of Toronto, Toronto, Ontario, Canada.
Technol Cancer Res Treat. 2009 Aug;8(4):271-80. doi: 10.1177/153303460900800404.
Stereotactic radiosurgery (SRS) refers to a single radiation treatment delivering a high dose to an intra-cranial target localized in three-dimensions by CT and/or MRI imaging. Traditionally, immobilization of the patient's head has been achieved using a rigid stereotactic head frame as the key step in allowing for accurate dose delivery. SRS has been delivered by both Cobalt-60 (Gamma Knife) and linear accelerator (linac) technologies for many decades. The focus of this review is to highlight recent advances and major innovations in SRS technologies relevant to clinical practice and developments allowing for non-invasive frame SRS.
立体定向放射外科（SRS）是指通过CT和/或MRI成像对颅内三维定位的靶点进行单次高剂量放射治疗。传统上，患者头部的固定是通过刚性立体定向头架来实现的，这是实现精确剂量输送的关键步骤。几十年来，钴-60（伽玛刀）和直线加速器（直线加速器）技术都用于进行SRS。本综述的重点是强调SRS技术在临床实践和非侵入性框架SRS发展方面的最新进展和重大创新。
