Gras-Cabrerizo J R, Montserrat-Gili J R, León-Vintró X, Massegur-Solench H, de Vega J M, Virós-Porcuna D
Department of Otolaryngology/Head and Neck Surgery, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Spain.
J Laryngol Otol. 2009 Oct;123(10):1120-4. doi: 10.1017/S0022215109990752. Epub 2009 Aug 3.
The aim of this study was to describe the results of treatment in patients with ethmoid sinus carcinoma.
We performed a retrospective study of 34 patients with carcinoma of the ethmoid sinus, and collected the following data: age, sex, employment, tobacco and alcohol consumption, tumour-node-metastasis stage, treatment, and survival.
The mean patient age was 64 years. Seventy-six per cent of patients were men and 24 per cent women. Squamous cell carcinoma was the most frequent histological tumour type (44 per cent). Eleven patients were classified as T(2), six as T(3), six as T(4a) and 11 as T(4b). Two patients (6 per cent) had nodal metastasis at the time of diagnosis. The anterior skull base was involved in 17 patients (50 per cent) and the anterior orbital contents were affected in seven patients (21 per cent). The five-year actuarial observed survival rate for all patients was 44 per cent.
Combined treatment with surgery and post-operative radiotherapy permitted good local control in patients with ethmoid sinus carcinoma. We do not recommend prophylactic neck treatment for ethmoid sinus carcinoma.
本研究旨在描述筛窦癌患者的治疗结果。
我们对34例筛窦癌患者进行了回顾性研究，并收集了以下数据：年龄、性别、职业、烟草和酒精消费情况、肿瘤-淋巴结-转移分期、治疗方法及生存情况。
患者的平均年龄为64岁。76%为男性，24%为女性。鳞状细胞癌是最常见的组织学肿瘤类型（44%）。11例患者被分类为T(2)，6例为T(3)，6例为T(4a)，11例为T(4b)。2例患者（6%）在诊断时出现淋巴结转移。17例患者（50%）累及前颅底，7例患者（21%）眼眶前部内容物受影响。所有患者的五年精算观察生存率为44%。
手术与术后放疗联合治疗可使筛窦癌患者获得良好的局部控制。我们不建议对筛窦癌进行预防性颈部治疗。
