Cloutier Robert L
Department of Emergency Medicine, Doernbecher Children's Hospital, Oregon Health & Science University, Portland, OR 97239, USA.
Emerg Med Clin North Am. 2009 Aug;27(3):415-22. doi: 10.1016/j.emc.2009.04.002.
Neutropenic enterocolitis, also known as typhlitis or ileocecal syndrome, is a rare but important complication of neutropenia associated with malignancy. It occurs as a result of chemotherapeutic damage to the intestinal mucosa in the context of an absolute neutropenia, and can rapidly progress to intestinal perforation, multisystem organ failure, and sepsis. Presenting signs and symptoms may include fever, abdominal pain, nausea, vomiting, and diarrhea. Rapid identification by emergency physicians and timely, aggressive medical and/or surgical intervention are the cornerstones of survival for these patients.
中性粒细胞减少性小肠结肠炎，又称盲肠炎或回盲部综合征，是一种与恶性肿瘤相关的中性粒细胞减少症的罕见但重要的并发症。它是在绝对中性粒细胞减少的情况下，由于化疗对肠黏膜造成损伤而发生的，可迅速发展为肠穿孔、多系统器官衰竭和败血症。出现的体征和症状可能包括发热、腹痛、恶心、呕吐和腹泻。急诊医生的快速识别以及及时、积极的药物和/或手术干预是这些患者生存的基石。
