Department of Emergency Medicine, Doernbecher Children's Hospital, Oregon Health & Science University, 3181 Sam Jackson Park Road, Portland, OR 97239, USA.
Hematol Oncol Clin North Am. 2010 Jun;24(3):577-84. doi: 10.1016/j.hoc.2010.03.005.
Neutropenic enterocolitis, also known as typhlitis or ileocecal syndrome, is a rare, but important, complication of neutropenia associated with malignancy. It occurs as a result of chemotherapeutic damage to the intestinal mucosa in the context of an absolute neutropenia and can rapidly progress to intestinal perforation, multisystem organ failure, and sepsis. Presenting signs and symptoms may include fever, abdominal pain, nausea, vomiting, and diarrhea. Rapid identification and timely, aggressive medical and/or surgical intervention are the cornerstones of survival for these patients.
中性粒细胞减少性肠炎，又称盲肠炎或回盲综合征，是一种与恶性肿瘤相关的中性粒细胞减少症伴发的罕见但重要的并发症。它是由于化疗药物对绝对中性粒细胞减少症患者的肠黏膜的损伤而引起的，并可迅速进展为肠穿孔、多器官功能衰竭和脓毒症。其临床表现包括发热、腹痛、恶心、呕吐和腹泻。快速识别并及时、积极的内科和/或外科干预是这些患者生存的关键。
