Kaneda Yasuhiro, Jayathilak Karuna, Meltzer Herbert Y
Department of Psychiatry, Iwaki Clinic, 11-1 Kamimizuta, Gakubara-cho, Anan-shi, Tokushima 774-0014, Japan.
Psychiatry Res. 2009 Sep 30;169(2):178-9. doi: 10.1016/j.psychres.2008.08.003. Epub 2009 Jul 30.
Cognitive impairment has been reported to be more important than clinical symptomatology as a determinant of work and social function in schizophrenia. In a retrospective analysis of a group of 152 patients with chronic schizophrenia or schizoaffective disorder, performance on a battery of neuropsychological tests was contrasted in employed (32, 21.1%) versus unemployed subgroups. As predicted, neurocognitive performance was more important than clinical symptoms in predicting employment status. Among neurocognitive functions, verbal working memory (as reflected by the Consonant Trigram Test) was the strongest predictor of employment status.
据报道，在精神分裂症中，认知障碍作为工作和社会功能的决定因素比临床症状更为重要。在一项对152例慢性精神分裂症或分裂情感性障碍患者的回顾性分析中，对一组神经心理学测试的表现进行了对比，该组患者分为就业亚组（32例，占21.1%）和失业亚组。正如所预测的那样，在预测就业状况方面，神经认知表现比临床症状更为重要。在神经认知功能中，言语工作记忆（由辅音连字测验反映）是就业状况的最强预测指标。
