Pierantoni Riccardo, Cobellis Gilda, Meccariello Rosaria, Cacciola Giovanna, Chianese Rosanna, Chioccarelli Teresa, Fasano Silvia
Dipartimento di Medicina Sperimentale, Seconda Università di Napoli, Via Costantinopoli, Napoli, Italy.
Vitam Horm. 2009;81:367-87. doi: 10.1016/S0083-6729(09)81014-5.
The importance of the endocannabinoid system (ECBS) and its involvement in several physiological processes is still increasing. Since the isolation of the main active compound of Cannabis sativa, Delta(9)-THC, several lines of research have evidenced the basic roles of this signaling system mainly considering its high conservation during evolution. In this chapter the attention is focussed on the involvement of the ECBS in the control of male reproductive aspects at both central and local levels which are both considered from a comparative point of view.
内源性大麻素系统（ECBS）的重要性及其在多种生理过程中的参与度仍在不断提高。自从大麻主要活性化合物Δ⁹-四氢大麻酚（Delta(9)-THC）被分离出来后，多条研究线路都证明了这个信号系统的基本作用，主要是考虑到其在进化过程中的高度保守性。在本章中，我们将重点关注内源性大麻素系统在中枢和局部水平对男性生殖方面的控制作用，并且从比较的角度对这两个层面进行探讨。
