Li Z
Zhonghua Yi Xue Za Zhi. 1990 Sep;70(9):491-3, 34.
HBsAg and HBcAg were detected in the liver biopsies of 21 patients with schistosomiasis japonica complicated by hepatocellular carcinoma (HCC), 69 patients with advanced schistosomiasis japonica and 25 patients with HCC. The positive rate of HBAg in liver of patients with schistosomiasis complicated by HCC (85.7%) was significantly higher than those with advanced schistosomiasis (56.5%), but similar to that in the group of HCC (80.0%). The location of tumor cells in liver was not related with the distribution of schistosomal ova in patients with schistosomiasis complicated by HCC. The results indicate that complicated HBV infection may be one of the major causes of HCC developed in patients with schistosomiasis japonica.
在21例日本血吸虫病合并肝细胞癌（HCC）患者、69例晚期日本血吸虫病患者和25例HCC患者的肝活检组织中检测到乙肝表面抗原（HBsAg）和乙肝核心抗原（HBcAg）。血吸虫病合并HCC患者肝脏中HBsAg的阳性率（85.7%）显著高于晚期血吸虫病患者（56.5%），但与HCC组（80.0%）相似。血吸虫病合并HCC患者肝脏中肿瘤细胞的位置与血吸虫卵的分布无关。结果表明，合并HBV感染可能是日本血吸虫病患者发生HCC的主要原因之一。
