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衡量精神病治疗的益处:EQ-5D的效度与反应度

Measuring the benefits of treatment for psychosis: validity and responsiveness of the EQ-5D.

作者信息

Barton Garry R, Hodgekins Jo, Mugford Miranda, Jones Peter B, Croudace Tim, Fowler David

机构信息

School of Medicine, Health Policy and Practice, University of East Anglia, Norwich NR4 7TJ, UK.

出版信息

Br J Psychiatry. 2009 Aug;195(2):170-7. doi: 10.1192/bjp.bp.108.057380.

Abstract

BACKGROUND

The UK National Institute for Health and Clinical Excellence (NICE) has recommended that cost-effectiveness analysis includes the EQ-5D; however, this is often not implemented in the area of mental health.

AIMS

To assess the appropriateness of using the EQ-5D to measure improvements in mental health.

METHOD

Seventy-seven participants with psychosis were rated according to the EQ-5D and seven measures of mental health at both pre- and post-intervention. To assess construct validity we compared the (pre-intervention) mean EQ-5D scores for those with milder and more severe scores, according to each of the seven measures. To assess responsiveness we estimated the mean EQ-5D change score for those who improved (post-intervention), according to each of the measures.

RESULTS

The mean EQ-5D score was more favourable for both those with milder scores (mean difference: 0.044 to 0.301) and for those who improved post-intervention (mean change: 0.029 to 0.117).

CONCLUSIONS

This suggests the EQ-5D should be considered for use in future cost-effectiveness studies in the area of mental health.

摘要

背景

英国国家卫生与临床优化研究所(NICE)建议成本效益分析应纳入EQ-5D;然而,在心理健康领域这一建议常常未得到执行。

目的

评估使用EQ-5D来衡量心理健康改善情况的适宜性。

方法

77名患有精神病的参与者在干预前后分别根据EQ-5D和七种心理健康测量方法进行评分。为评估结构效度,我们根据七种测量方法中的每一种,比较了病情较轻和较重参与者(干预前)的平均EQ-5D得分。为评估反应度,我们根据每一种测量方法,估算了干预后病情有所改善的参与者的平均EQ-5D变化得分。

结果

对于病情较轻的参与者(平均差异:0.044至0.301)以及干预后病情有所改善的参与者(平均变化:0.029至0.117),平均EQ-5D得分均更为有利。

结论

这表明在未来心理健康领域的成本效益研究中应考虑使用EQ-5D。

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