Rifat Mannan Abul Ala Syed, Kahvic Mirza, Abu Sara Yahya, Bharati Chandramouli
Department of Pathology, Al Jahra Hospital, Jahra, Kuwait.
Med Princ Pract. 2009;18(5):418-21. doi: 10.1159/000226299. Epub 2009 Jul 31.
We report an unusual case of extensive xanthogranulomatous orchitis (XGO) in association with poorly controlled diabetes mellitus.
A 65-year-old Kuwaiti man with poorly controlled diabetes mellitus presented with a painful left testicular swelling of 1 year duration. Testicular tumor markers were normal. Scrotal ultrasonography showed a mass lesion of mixed echotexture, which almost replaced the testicular parenchyma. Left-sided orchiectomy was performed with the clinical diagnosis of testicular neoplasia. Subsequent examination revealed the diagnosis of XGO, and the patient is well 2 years after the operation.
Extensive tumorous XGO associated with diabetes mellitus has not been previously reported. We offer this case to highlight the implied role of poorly controlled diabetes mellitus in the pathogenesis of XGO.
我们报告一例罕见的广泛性黄色肉芽肿性睾丸炎（XGO）合并糖尿病控制不佳的病例。
一名65岁的科威特男性，糖尿病控制不佳，左侧睾丸疼痛性肿大1年。睾丸肿瘤标志物正常。阴囊超声显示混合回声的肿块病变，几乎取代了睾丸实质。临床诊断为睾丸肿瘤，遂行左侧睾丸切除术。随后的检查确诊为XGO，患者术后2年情况良好。
此前尚未报道过与糖尿病相关的广泛性肿瘤性XGO。我们提供此病例以强调糖尿病控制不佳在XGO发病机制中的潜在作用。
