Romics I, Rüssel C, Bach D
Department of Urology, St. Agnes Hospital, Bocholt, FRG.
Int Urol Nephrol. 1990;22(6):507-12. doi: 10.1007/BF02549737.
The hormone receptor concentrations in tumour tissues from 20 renal carcinoma patients were determined before postoperative medroxyprogesterone acetate (MPA) therapy was started. Except for glucocorticoid receptors, the concentrations were either not measurable or were extremely low. The question is whether MPA therapy, solely on the strength of its character as a general roborant, is still useful in the treatment of renal tumours, even when it fails to exercise primary influence because of the absence of suitable receptors. None of the 20 patients was treated with MPA.
在20例肾癌患者术后开始醋酸甲羟孕酮(MPA)治疗前,测定了其肿瘤组织中的激素受体浓度。除糖皮质激素受体外,其他受体浓度要么无法测定,要么极低。问题在于,即使MPA因缺乏合适受体而无法发挥主要作用,仅凭借其作为一般强壮剂的特性,MPA治疗在肾肿瘤治疗中是否仍有用。这20例患者均未接受MPA治疗。