Di Fronzo G, Ronchi E, Bertuzzi A, Vezzoni P, Pizzocaro G
Eur Urol. 1980;6(5):307-11. doi: 10.1159/000473359.
The presence of estrogen receptors was determined in 31 cases of renal carcinoma by use of the charcoal absorption technique. In 26 of these cases, the 'normal' counterpart of the same kidney was also studied. In 13 normal and in 19 neoplastic samples, the values were undetectable; in the other cases, the values were very low. Progesterone and dihydrotestosterone receptors were also studied in four cses (both normal and neoplastic tissue) by use of a gel-filtration assay: all the samples were negative. These findings do not support the presence of significant amounts of estrogen receptors in kidney carcinoma.
采用活性炭吸附技术对31例肾癌患者的雌激素受体情况进行了测定。其中26例患者,对其同一侧肾脏的“正常”组织也进行了研究。在13例正常样本和19例肿瘤样本中,均未检测到相应受体值;在其他病例中,受体值非常低。还采用凝胶过滤分析法对4例(包括正常和肿瘤组织)患者的孕激素和双氢睾酮受体进行了研究:所有样本均为阴性。这些研究结果不支持肾癌中存在大量雌激素受体这一观点。