Torrisi A, Giorgino F, Onnis G L, Minucci D
Obstet. Gynec. Institute, University of Padua, Italy.
Eur J Gynaecol Oncol. 1990;11(5):343-6.
The Authors have reported the cytological patterns of malignant primitive uterine fibrous histiocytoma of a 57 year old woman. The endometrial cytological sampling was performed by an aspiration technique using a feeding-tube; a necrotic-haemorrhagic background filled with hymphocytes and polymorphonuclear leukocytes, and a mixture of highly anaplastic histiocytic and fibroblastic type cells, associated with undifferentiated small round cells, has been described. The result of the histological examination performed on the surgical specimen was the following: polymorphic malignant neoplasia characterized by spindle-like and giant plurinucleated cells, phagocytosis features, endoluminal polypoid growth, wide infiltration of the miometrium two thirds deep, vascular space invasion of the uterine wall and the hilus of the ovaries. The histological features and immunohistochemical analysis were consistent with malignant fibrous histiocytoma in the pleomorphic variety.
作者报道了一名57岁女性的恶性原发性子宫纤维组织细胞瘤的细胞学特征。采用饲管吸取技术进行子宫内膜细胞学取样；描述了一个充满淋巴细胞和多形核白细胞的坏死性出血背景，以及高度间变的组织细胞和成纤维细胞类型细胞的混合物，伴有未分化的小圆形细胞。对手术标本进行组织学检查的结果如下：多形性恶性肿瘤，其特征为梭形和巨大的多核细胞、吞噬特征、腔内息肉样生长、子宫肌层三分之二深度的广泛浸润、子宫壁和卵巢门的血管间隙侵犯。组织学特征和免疫组化分析与多形性恶性纤维组织细胞瘤一致。
