高比放射性氚标记人促肾上腺皮质激素的合成。
The synthesis of tritium-labelled human corticotropin of high specific radioactivity.
作者信息
Brundish D E, Wade R
出版信息
Biochem J. 1977 Jul 1;165(1):169-71. doi: 10.1042/bj1650169.
Abstract
Human [[3,5-3H2]Tyr23]corticotropin-(1-39)-nonatriacontapeptide of specific radioactivity 25.2 Ci/mmol, identical with unlabelled human corticotropin by several criteria, was prepared via the fully protected di-iodotyrosine compound. The latter was synthesized by classical procedures.
摘要
通过完全保护的二碘酪氨酸化合物制备了比放射性为25.2 Ci/mmol的人[[3,5-³H₂]酪氨酸²³]促肾上腺皮质激素-(1-39)-三十九肽，通过几个标准与未标记的人促肾上腺皮质激素相同。后者通过经典方法合成。
相似文献
1
The synthesis of tritium-labelled human corticotropin of high specific radioactivity.高比放射性氚标记人促肾上腺皮质激素的合成。
Biochem J. 1977 Jul 1;165(1):169-71. doi: 10.1042/bj1650169.
2
The synthesis of beta corticotrophin-(1-24)-tetracosapeptide (synacthen) of high specific radioactivity.高比放射性β-促肾上腺皮质激素-（1-24）-二十四肽（合成促皮质素）的合成。
Biochem J. 1972 Sep;129(2):23P. doi: 10.1042/bj1290023pa.
3
Preparation of radiolabeled neuroendocrine peptides.放射性标记神经内分泌肽的制备。
Methods Enzymol. 1983;103:32-48. doi: 10.1016/s0076-6879(83)03004-9.
4
Measurement of specific radioactivities in labelled hormones by self-displacement analysis.通过自置换分析法测定标记激素中的比放射性。
Biochem J. 1983 May 15;212(2):259-64. doi: 10.1042/bj2120259.
5
[Tritium labeling of tRNA by the tritium thermal activation method].[用氚热激活法对转运核糖核酸进行氚标记]
Bioorg Khim. 1985 Jul;11(7):948-52.
6
Preparation and characterization of specifically tritiated adrenocorticotropin.特异性氚标记促肾上腺皮质激素的制备与表征
Biochim Biophys Acta. 1977 Feb 28;496(2):321-8. doi: 10.1016/0304-4165(77)90314-2.
7
A route to tritium labelled 11-methyl prostaglandins.一种制备氚标记的11-甲基前列腺素的方法。
Prostaglandins. 1981 Apr;21(4):615-22. doi: 10.1016/0090-6980(81)90010-1.
8
Synthesis of tritium-labelled isopenicillin N, penicillin N and 6-aminopenicillanic acid.氚标记的异青霉素N、青霉素N和6-氨基青霉烷酸的合成。
Biochem J. 1975 Dec;151(3):729-39. doi: 10.1042/bj1510729.
9
Tritiated peptides. Part 2. Synthesis of two [3,5-3H2-Tyr2]-analogues of corticotrophin.氚标记的肽。第2部分。两种促肾上腺皮质激素的[3,5 - 3H₂ - 酪氨酸²]类似物的合成。
J Chem Soc Perkin 1. 1976(20):2182-5. doi: 10.1039/p19760002182.
10
[Synthesis of tritium-labelled prostaglandin E1 and its binding to human platelets].[氚标记前列腺素E1的合成及其与人血小板的结合]
Bioorg Khim. 1988 Aug;14(8):1075-85.
引用本文的文献
1
A rapid method, using octadecasilyl-silica, for the extraction of certain peptides from tissues.一种使用十八烷基硅烷化硅胶从组织中提取某些肽的快速方法。
Biochem J. 1978 Dec 1;175(3):1139-41. doi: 10.1042/bj1751139.
本文引用的文献
1
Purification and some properties of prolidase of swine kidney.猪肾氨肽酶的纯化及某些性质
J Biol Chem. 1957 Jan;224(1):261-75.
2
Norephedrines as metabolites of ( 14 C)amphetamine in urine in man.去甲麻黄碱作为人体尿液中（14C）苯丙胺的代谢产物。
Biochem J. 1972 Aug;129(1):23-4. doi: 10.1042/bj1290023.
3
Fate of corticotrophins in an isolated adrenal-cell bioassay and decrease of peptide breakdown by cell purification.促肾上腺皮质激素在离体肾上腺细胞生物测定中的命运以及细胞纯化导致的肽降解减少
Biochem J. 1974 Feb;138(2):185-94. doi: 10.1042/bj1380185.
4
Properties of a simplified bioassay for adrenocorticotrophic activity using the steroidogenic response of isolated adrenal cells.利用分离肾上腺细胞的类固醇生成反应对促肾上腺皮质激素活性进行简化生物测定的特性。
J Endocrinol. 1973 Oct;59(1):43-55. doi: 10.1677/joe.0.0590043.
5
Complete amino acid analysis of peptides and proteins after hydrolysis by a mixture of sepharose-bound peptidases.用琼脂糖结合肽酶混合物水解后对肽和蛋白质进行完整氨基酸分析。
Biochem J. 1972 Sep;129(3):695-701. doi: 10.1042/bj1290695.
6
[Synthesis of the human adrenal cortex hormone ( h ACTH) with a revised amino acid sequence].[具有修正氨基酸序列的人肾上腺皮质激素（hACTH）的合成]
Helv Chim Acta. 1972;55(4):1243-66. doi: 10.1002/hlca.19720550420.
7
On the metabolism of two adrenocorticotrophin analogues.关于两种促肾上腺皮质激素类似物的代谢
Clin Endocrinol (Oxf). 1976;5 Suppl:61S-72S. doi: 10.1111/j.1365-2265.1976.tb03816.x.
8
Adrenocorticotropin. 51. Synthesis and properties of analogues of the human hormone with tyrosine residues replaced by 3,5-diiodotyrosine.促肾上腺皮质激素。51. 酪氨酸残基被3,5-二碘酪氨酸取代的人激素类似物的合成与性质。
J Am Chem Soc. 1977 Mar 2;99(5):1577-80. doi: 10.1021/ja00447a048.
9
Tritiated peptides. Part 2. Synthesis of two [3,5-3H2-Tyr2]-analogues of corticotrophin.氚标记的肽。第2部分。两种促肾上腺皮质激素的[3,5 - 3H₂ - 酪氨酸²]类似物的合成。
J Chem Soc Perkin 1. 1976(20):2182-5. doi: 10.1039/p19760002182.
Zotero 插件