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对于慢性 Stanford A 型主动脉夹层患者,全弓置换联合带支架象鼻植入术是否合理?

Is total arch replacement combined with stented elephant trunk implantation justified for patients with chronic Stanford type A aortic dissection?

作者信息

Sun Li-Zhong, Qi Rui-Dong, Chang Qian, Zhu Jun-Ming, Liu Yong-Min, Yu Chun-Tao, Lv Bin, Zheng Jun, Tian Liang-Xin, Lu Jin-Guo

机构信息

Department of Cardiovascular Surgery, Cardiovascular Institute and Fuwai Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China.

出版信息

J Thorac Cardiovasc Surg. 2009 Oct;138(4):892-6. doi: 10.1016/j.jtcvs.2009.02.041. Epub 2009 Apr 25.

DOI:10.1016/j.jtcvs.2009.02.041
PMID:19660358
Abstract

OBJECTIVE

Surgical treatment of chronic Stanford type A aortic dissection using total arch replacement combined with stented elephant trunk implantation is controversial owing to the visceral arteries and intercostal arteries originating from the false lumen.

METHODS

Eighty-nine patients (mean age, 45.67 +/- 10.18 years; range, 21-68 years) with chronic type A dissection underwent total arch replacement combined with stented elephant trunk implantation between April 2003 and March 2007. Careful assessment of the visceral arteries and location of entry and re-entry was done before surgery. Postoperative patency of the visceral arteries and diameter of the aortic artery and the residual false lumen were evaluated by computed tomography.

RESULTS

One (1.12%) hospital death and 2 (2.25%) late deaths occurred at a mean follow-up of 28.5 months (range, 8-52 months). Visceral malperfusion was not observed. Two patients had spinal cord injury and recovered during follow-up. One patient had a transient neurologic deficit and recovered completely before discharge. One patient underwent thoracoabdominal aortic replacement for aneurysmal dilatation of the residual descending aorta 3 months after the operation. Thrombus obliteration of the false lumen at the distal edge of the stented elephant trunk and at the diaphragmatic level was 94.2% (81/86) and 61.6% (53/86), respectively.

CONCLUSIONS

Satisfactory results with low morbidity and mortality were obtained. No visceral malperfusion and a low risk of postoperative spinal cord injury favor this technique in patients with chronic type A dissection.

摘要

目的

由于内脏动脉和肋间动脉起源于假腔,采用全弓置换联合带支架象鼻植入术治疗慢性Stanford A型主动脉夹层存在争议。

方法

2003年4月至2007年3月期间,89例(平均年龄45.67±10.18岁;范围21 - 68岁)慢性A型夹层患者接受了全弓置换联合带支架象鼻植入术。术前仔细评估内脏动脉以及入口和再入口的位置。术后通过计算机断层扫描评估内脏动脉的通畅情况、主动脉直径和残余假腔。

结果

平均随访28.5个月(范围8 - 52个月),发生1例(1.12%)医院死亡和2例(2.25%)晚期死亡。未观察到内脏灌注不良。2例患者发生脊髓损伤,随访期间恢复。1例患者有短暂性神经功能缺损,出院前完全恢复。1例患者术后3个月因残余降主动脉瘤样扩张接受胸腹主动脉置换。带支架象鼻远端边缘和膈肌水平假腔的血栓闭塞率分别为94.2%(81/86)和61.6%(53/86)。

结论

获得了低发病率和死亡率的满意结果。无内脏灌注不良且术后脊髓损伤风险低,使得该技术适用于慢性A型夹层患者。

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