Chang Shih-Heng, Huang Chien-Hua, Shih Chung-Liang, Lee Chien-Chang, Chang Wei-Tien, Chen Yu-Tsung, Lee Chiao-Hao, Lin Zhi-Yi, Tsai Min-Shan, Hsu Chiung-Yuan, Ma Matthew Huei-Ming, Chen Shyr-Chyr, Chen Wen-Jone
Department of Emergency Medicine, National Taiwan University Hospital Yun-Lin Branch, Douliou, Taipei 100, Taiwan.
J Crit Care. 2009 Sep;24(3):408-14. doi: 10.1016/j.jcrc.2008.10.006.
The aim of this study was to evaluate the factors related to outcome regarding in-intensive care unit (ICU) cardiac arrest (IICA) in a university hospital.
Adult nontraumatic ICU patients who sustained IICA were prospectively enrolled. Several patient and event-related variables, as well as outcomes, were recorded and summarized based on the revised Utstein-style template.
A total of 202 episodes of IICA happened during the study period. Return of spontaneous circulation (ROSC) was achieved in 127 patients (62.9%), whereas the overall survival-to-discharge rate was 15.3% (31 patients). In univariate analysis, a shorter duration of resuscitation and pulseless ventricular tachycardia/ventricular fibrillation (VT/VF) as initial arrest rhythm represented better outcomes. Independent predictors of survival to hospital discharge were VT/VF as the initial rhythm (odds ratio [OR], 3.81; 95% confidence interval [CI], 1.50-9.67; P = .005), lower Acute Physiology and Chronic Health Evaluation II score (OR 0.92, 95% CI 0.87-0.98, P = .008), and shorter resuscitation durations (OR 0.91, 95% CI 0.87-0.96, P < .001).
Shorter resuscitation duration and initial VT/VF are predictors for both ROSC and hospital survival, whereas lower Acute Physiology and Chronic Health Evaluation II scores predict the latter.