Dorset Research and Development Support Unit, Poole Hospital NHS Foundation Trust, Poole, Dorset BH15 2JB, UK.
Patient Educ Couns. 2010 Feb;78(2):240-9. doi: 10.1016/j.pec.2009.07.001. Epub 2009 Aug 7.
(i) To develop a group-based intervention for the management of multiple sclerosis (MS) fatigue incorporating energy effectiveness and cognitive behavioural approaches and (ii) to undertake a process and preliminary evaluation.
Drawing upon a literature search, a local model of good practice and the views of service users and health professionals, a manualised group-based fatigue management programme was developed, designed to be delivered by health professionals. A process and preliminary outcome evaluation was undertaken. Sixteen participants attended across two iterations. Participant feedback, obtained via a focus group and evaluation questionnaires, was used to refine the programme. Outcomes were collected pre- and post-programme (including fatigue severity, quality of life, self-efficacy).
Focus group feedback suggested the programme was well received, reflected in high attendance and positive ratings on evaluation questionnaires. At follow-up, despite the small sample size, there were significant improvements in perceived self-efficacy for managing fatigue.
An evidence-based fatigue management intervention has been developed and preliminary findings look promising. In the next phase we will examine whether the programme transfers satisfactorily to other centres and collect data in preparation for a randomised controlled trial (RCT).
Implications for practice will emerge when the results of our RCT are published.
（一）制定一项基于小组的多发性硬化症（MS）疲劳管理干预措施，纳入能量效率和认知行为方法；（二）进行过程和初步评估。
通过文献检索、当地良好实践模式以及服务使用者和卫生专业人员的观点，开发了一种基于手册的小组疲劳管理方案，旨在由卫生专业人员提供。进行了过程和初步结果评估。两个迭代中共有 16 名参与者参加。通过焦点小组和评估问卷获得的参与者反馈用于改进方案。在方案前后收集了结果（包括疲劳严重程度、生活质量、自我效能感）。
焦点小组的反馈表明该方案反应良好，反映在高出勤率和评估问卷上的积极评分。随访时，尽管样本量较小，但在管理疲劳的自我效能感方面有显著改善。
已经开发了一种基于证据的疲劳管理干预措施，初步结果看起来很有希望。下一阶段，我们将研究该方案是否能在其他中心顺利转移，并收集数据为随机对照试验（RCT）做准备。
当我们的 RCT 结果公布时，将出现实践意义。
